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B0TAF2 (B0TAF2_HELMI) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Deoxyribose-phosphate aldolase HAMAP MF_00114

Short name=DERA HAMAP MF_00114
EC=4.1.2.4 HAMAP MF_00114
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase HAMAP MF_00114
Phosphodeoxyriboaldolase HAMAP MF_00114
Gene names
Name:deoC HAMAP MF_00114 EMBL ABZ85002.1
Ordered Locus Names:Helmi_23770
ORF Names:HM1_2452 EMBL ABZ85002.1
OrganismHeliobacterium modesticaldum (strain ATCC 51547 / Ice1) [Complete proteome] [HAMAP]
Taxonomic identifier498761 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesHeliobacteriaceaeHeliobacterium

Protein attributes

Sequence length241 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114 SAAS SAAS022979

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114 SAAS SAAS022979

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114 SAAS SAAS022979

Subcellular location

Cytoplasm By similarity HAMAP MF_00114 SAAS SAAS022979.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. HAMAP MF_00114

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1681Schiff-base intermediate with acetaldehyde By similarity HAMAP MF_00114
Active site1971 By similarity HAMAP MF_00114

Sequences

Sequence LengthMass (Da)Tools
B0TAF2 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: BE60DD5D6693C7EB

FASTA24125,367
        10         20         30         40         50         60 
MIAVSFQTGD RWTRERVAPL IDHTLLKPDA KEVQIEALCR EAATYGFAAV CVNPVWVETC 

        70         80         90        100        110        120 
AALLQGSPVK VATVIGFPLG ASLSRVKALE AREALRSGAL ELDMVMNMGW AKMGRWDAIE 

       130        140        150        160        170        180 
ADIAAVVEEA RRMPGAVVKV ILETALLTDE EITVACHRAL NAGADYVKTS TGFGPGGATT 

       190        200        210        220        230        240 
AHVSLMAETV RGRARVKASG GIRTAERAVR MLEAGADRLG TSASLVILDG LPGAAGVSLS 


R 

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References

[1]"The genome of Heliobacterium modesticaldum, a phototrophic representative of the Firmicutes containing the simplest photosynthetic apparatus."
Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M., Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T., Raymond J., Chen M., Blankenship R.E., Touchman J.W.
J. Bacteriol. 190:4687-4696(2008) [PubMed: 18441057] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000930 Genomic DNA. Translation: ABZ85002.1.
RefSeqYP_001681013.1. NC_010337.2.

3D structure databases

ProteinModelPortalB0TAF2.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0TAF2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5910498.
GenomeReviewsGene locus Helmi_23770 in contig CP000930_GR.
KEGGhmo:HM1_2452.
PATRIC22108989. VBIHelMod36755_2217.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG636421.
OMACLEAREN.

Family and domain databases

HAMAPMF_00114. DeoC_type1.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/AroFGH_arch.
IPR022979. Deoxyribose_phosphate_aldo_1.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01619.
PANTHERPTHR10889. DeoC. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. DeoC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB0TAF2_HELMI
AccessionPrimary (citable) accession number: B0TAF2
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)