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Protein

tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

Gene

mnmG

Organism
Heliobacterium modesticaldum (strain ATCC 51547 / Ice1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.UniRule annotation

Cofactori

FADUniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei127 – 1271FAD; via amide nitrogen and carbonyl oxygenUniRule annotation
Binding sitei182 – 1821FADUniRule annotation
Binding sitei371 – 3711FADUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 206FADUniRule annotation
Nucleotide bindingi274 – 28815NADUniRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

FAD, Flavoprotein, NAD

Enzyme and pathway databases

BioCyciHMOD498761:GI46-1056-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGUniRule annotation
Alternative name(s):
Glucose-inhibited division protein AUniRule annotation
Gene namesi
Name:mnmGUniRule annotation
Synonyms:gidAUniRule annotation
Ordered Locus Names:Helmi_10270
ORF Names:HM1_0913
OrganismiHeliobacterium modesticaldum (strain ATCC 51547 / Ice1)
Taxonomic identifieri498761 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesHeliobacteriaceaeHeliobacterium
ProteomesiUP000008550 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 637637tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGPRO_0000345279Add
BLAST

Interactioni

Subunit structurei

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.UniRule annotation

Protein-protein interaction databases

STRINGi498761.HM1_0913.

Structurei

3D structure databases

ProteinModelPortaliB0TAB5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0445.
HOGENOMiHOG000201060.
KOiK03495.
OMAiYINGLST.
OrthoDBiEOG6W9X6J.

Family and domain databases

HAMAPiMF_00129. MnmG_GidA.
InterProiIPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0TAB5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEYVAGKYD VIVIGAGHAG CEAALASARL GAKTLILTIS WDNVALMPCN
60 70 80 90 100
PAIGGPAKGH LVREIDALGG QMGLTIDKTC IQIRLLNTGK GPAVHALRAQ
110 120 130 140 150
ADKKRYQREM IRVLEHQENL DVRQAMVESV VVEQGRVRGI RTNTGAFFAA
160 170 180 190 200
PALVITTGTY LRGRIIIGDL HYPGGPNGYF PSVALAASLR DIGVRLGRFK
210 220 230 240 250
TGTPARVDGR TVDFSQMVEQ PGDREPLNFS FLSPRIERKQ ISCWLTYTTE
260 270 280 290 300
ETHQIIRDNL HRSPLYAGVI EGTGPRYCPS IEDKVVRFAD KKSHQVFIEP
310 320 330 340 350
EGEGTHEMYV QGMSTSLPED VQVTMLRSII GMKDVKIIRP GYAIEYDYVD
360 370 380 390 400
PTQLRLSLEH QEIGGLFTAG QINGTSGYEE AAAQGLMAGI NAARFVKGEE
410 420 430 440 450
PLVLKRSDAY IGVLIDDLVT KGTNEPYRML TSRAEYRLLL RQDNADQRLT
460 470 480 490 500
EIGRSIGLVD DRRYRRFREK MQLLEQEVVR WKSSFVTPGN KKIQAILDEK
510 520 530 540 550
KSAPLTKGVS LYDLLRRPEL TYDDLIPLCN DGEKDLPIDP EVAEQVEISA
560 570 580 590 600
KFEGYLVKQQ AQVDRFNKLE NKRLPADLDY KRVHGLSNEG RQKLIARKPV
610 620 630
SIGQASRISG VSPADISILL VYLEQQRRLA PGEGGVD
Length:637
Mass (Da):70,779
Last modified:April 8, 2008 - v1
Checksum:i8F06F9D4DB674263
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000930 Genomic DNA. Translation: ABZ83652.1.
RefSeqiWP_012282175.1. NC_010337.2.
YP_001679663.1. NC_010337.2.

Genome annotation databases

EnsemblBacteriaiABZ83652; ABZ83652; HM1_0913.
KEGGihmo:HM1_0913.
PATRICi22106309. VBIHelMod36755_0947.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000930 Genomic DNA. Translation: ABZ83652.1.
RefSeqiWP_012282175.1. NC_010337.2.
YP_001679663.1. NC_010337.2.

3D structure databases

ProteinModelPortaliB0TAB5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi498761.HM1_0913.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABZ83652; ABZ83652; HM1_0913.
KEGGihmo:HM1_0913.
PATRICi22106309. VBIHelMod36755_0947.

Phylogenomic databases

eggNOGiCOG0445.
HOGENOMiHOG000201060.
KOiK03495.
OMAiYINGLST.
OrthoDBiEOG6W9X6J.

Enzyme and pathway databases

BioCyciHMOD498761:GI46-1056-MONOMER.

Family and domain databases

HAMAPiMF_00129. MnmG_GidA.
InterProiIPR004416. GidA.
IPR026904. GidA-assoc_3.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc_3. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of Heliobacterium modesticaldum, a phototrophic representative of the Firmicutes containing the simplest photosynthetic apparatus."
    Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M., Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T., Raymond J., Chen M., Blankenship R.E., Touchman J.W.
    J. Bacteriol. 190:4687-4696(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51547 / Ice1.

Entry informationi

Entry nameiMNMG_HELMI
AccessioniPrimary (citable) accession number: B0TAB5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: April 8, 2008
Last modified: May 27, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.