B0T9E6 (B0T9E6_CAUSK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase 2 HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2-2 HAMAP MF_01902
Ordered Locus Names:	Caul_5201

Encoded on

Plasmid pCAUL01 EMBL ABZ74321.1

Organism

Caulobacter sp. (strain K31) [Complete proteome] [HAMAP]

Taxonomic identifier

366602 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter

Protein attributes

Sequence length	1053 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome Plasmid EMBL ABZ74321.1
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0T9E6 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: CEBEF54C1B43F2D5	FASTA	1,053	117,133
	10 20 30 40 50 60 MSLPDPDDLG PYVELQCASH FSLLRGASSP GELFDEAQRL GYRALAICDR NSVAGVVRAH 70 80 90 100 110 120 IAAKATGVRL IIGCELVLRC GLTLVVLPTD RAAYGRLCRL LSLGKSRAGK GQCDLGLEDL 130 140 150 160 170 180 AAHAQGLIAI LVPDAPDDLC ALQLKKVAAI FGVDAHLALT LRRRPGDALR LHQLEAMARQ 190 200 210 220 230 240 AGVRPVVTNR VLFHEKGRRL LQDVVTCIRE GTTIDDVGFK RDRHADRYLK APSEIQRLLA 250 260 270 280 290 300 KHPDAVTASV EIARRCRFSL DELSYQYPHE VSEPGRTPQE TLERLTWFGA AQRYPDGLPA 310 320 330 340 350 360 EVEKALAHEL RLIGLLGYAP YFLTVNSIVQ YARGQDILCQ GRGSAANSAV CYVLGVTSID 370 380 390 400 410 420 PERNDLLFER FVSQERNEPP DIDVDFEHER RETVMQWIFE TYGRHRCALV AVVQRFRPRG 430 440 450 460 470 480 AVRDVGKVLG LPEDMTKALS SQIWSFSRED IEESHARDVG LDLSDRRLRL TLELAQLLLN 490 500 510 520 530 540 TPRHFSQHPG GFVLTEDRLD ELVPIEPARM QDRQIIEWDK DDIDELKFMK VDVLALGMLT 550 560 570 580 590 600 CLKRGLDLLA AHKDIHKDLA TIPPEDPRTY AMIRKADTLG VFQIESRAQM VMLPRLKPRS 610 620 630 640 650 660 FYDLVIEVAI VRPGPIQGDM VHPYLRRREG KEKVSYPKPE LEKVLGKTLG VPLFQEQAMR 670 680 690 700 710 720 VAIECAGFTP GEADQLRRSM ATFKMTGGVS HFRQKLLGGM VARGYPQDFA EQTFSQLEGF 730 740 750 760 770 780 GSYGFPESHA ASFALLAYAS SWLKCHHPDV FCAALLNSQP MGFYQPAQIV RDAVEHGVQI 790 800 810 820 830 840 RPICVNASRW DCTLEPDGDT GRLAVRLGMR LVKGLADGDA AALVLARGEE PYRSIDEVWR 850 860 870 880 890 900 RSGAKPGVLG RLAEADAFLP SLGLARREAA WAIKALRDDA LPLFDQPGAS ELNEPAVALK 910 920 930 940 950 960 AMTEGREIVE DYSHVGLSLR RHPLALLRSD LTRLRRAPCR DVAQGRDGRF IQTAGLVLVR 970 980 990 1000 1010 1020 QMPGSAKGVL FMTLEDETGV ANLVVWKTLY EKQRRIALGA HLLGVDGRIQ REGEVVHLVA 1030 1040 1050 YKLHDLGHVM AGLEDRSGDP ADMAWAKRSR NFC

References

[1]

"Complete sequence of plasmid1 pCAUL01 of Caulobacter sp. K31." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Thompson L.S., Brettin T., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Kim E., Stephens C., Richardson P. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K31.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000928 Genomic DNA. Translation: ABZ74321.1.
RefSeq	YP_001676635.1. NC_010335.1.
3D structure databases
ProteinModelPortal	B0T9E6.
ModBase	Search...
Protein-protein interaction databases
STRING	B0T9E6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5897253.
GenomeReviews	Gene locus Caul_5201 in contig CP000928_GR.
KEGG	cak:Caul_5201.
PATRIC	21312821. VBICauSp18104_0286.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	ADYCANG.
ProtClustDB	CLSK881842.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0T9E6_CAUSK

Accession

Primary (citable) accession number: B0T9E6

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)