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Protein

Glutamate racemase

Gene

murI

Organism
Caulobacter sp. (strain K31)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Provides the (R)-glutamate required for cell wall biosynthesis.UniRule annotation

Catalytic activityi

L-glutamate = D-glutamate.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei70 – 701Proton donor/acceptorUniRule annotation
Active sitei206 – 2061Proton donor/acceptorUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciCSP366602:GH0Y-4928-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate racemaseUniRule annotation (EC:5.1.1.3UniRule annotation)
Gene namesi
Name:murIUniRule annotation
Ordered Locus Names:Caul_4875
OrganismiCaulobacter sp. (strain K31)
Taxonomic identifieri366602 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
Proteomesi
  • UP000001316 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 283283Glutamate racemasePRO_1000078556Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi366602.Caul_4875.

Structurei

3D structure databases

ProteinModelPortaliB0T549.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni7 – 82Substrate bindingUniRule annotation
Regioni39 – 402Substrate bindingUniRule annotation
Regioni71 – 722Substrate bindingUniRule annotation
Regioni207 – 2082Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the aspartate/glutamate racemases family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105F03. Bacteria.
COG0796. LUCA.
HOGENOMiHOG000262396.
KOiK01776.
OMAiTEERIYS.
OrthoDBiPOG091H00P1.

Family and domain databases

Gene3Di3.40.50.1860. 1 hit.
HAMAPiMF_00258. Glu_racemase. 1 hit.
InterProiIPR015942. Asp/Glu/hydantoin_racemase.
IPR001920. Asp/Glu_race.
IPR018187. Asp/Glu_racemase_AS_1.
IPR004391. Glu_race.
[Graphical view]
PfamiPF01177. Asp_Glu_race. 1 hit.
[Graphical view]
SUPFAMiSSF53681. SSF53681. 2 hits.
PROSITEiPS00923. ASP_GLU_RACEMASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0T549-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIGVFDSGV GGLTVHRALV NRLPQADFIY LADQANAPYG GRPGEEIVAL
60 70 80 90 100
TRAGCERLFD AGASLVVLAC NTASAIALRR LQQTWLPGYR KALGRPINVL
110 120 130 140 150
GIIVPTIEAA TGLPWEHEAE RRGEKVEQLD ILGVFSTPGT AASRVYEIEI
160 170 180 190 200
DKRRQDVAVF SEPCPNLARM IEAGAGAVEL ATEVERHVQQ LKTRIGRYPD
210 220 230 240 250
RAILGCTHYE IIADLFRAAL PAGTPLIHQP ASTADALELY FQRHPELDPG
260 270 280
TGGGRVFLTT GTPGPQNALV ETFWGGPLRF EAA
Length:283
Mass (Da):30,529
Last modified:April 8, 2008 - v1
Checksum:i141EC66D8DA6F169
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000927 Genomic DNA. Translation: ABZ73995.1.
RefSeqiWP_012288866.1. NC_010338.1.

Genome annotation databases

EnsemblBacteriaiABZ73995; ABZ73995; Caul_4875.
KEGGicak:Caul_4875.
PATRICi21322936. VBICauSp18104_5290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000927 Genomic DNA. Translation: ABZ73995.1.
RefSeqiWP_012288866.1. NC_010338.1.

3D structure databases

ProteinModelPortaliB0T549.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi366602.Caul_4875.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABZ73995; ABZ73995; Caul_4875.
KEGGicak:Caul_4875.
PATRICi21322936. VBICauSp18104_5290.

Phylogenomic databases

eggNOGiENOG4105F03. Bacteria.
COG0796. LUCA.
HOGENOMiHOG000262396.
KOiK01776.
OMAiTEERIYS.
OrthoDBiPOG091H00P1.

Enzyme and pathway databases

UniPathwayiUPA00219.
BioCyciCSP366602:GH0Y-4928-MONOMER.

Family and domain databases

Gene3Di3.40.50.1860. 1 hit.
HAMAPiMF_00258. Glu_racemase. 1 hit.
InterProiIPR015942. Asp/Glu/hydantoin_racemase.
IPR001920. Asp/Glu_race.
IPR018187. Asp/Glu_racemase_AS_1.
IPR004391. Glu_race.
[Graphical view]
PfamiPF01177. Asp_Glu_race. 1 hit.
[Graphical view]
SUPFAMiSSF53681. SSF53681. 2 hits.
PROSITEiPS00923. ASP_GLU_RACEMASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMURI_CAUSK
AccessioniPrimary (citable) accession number: B0T549
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: September 7, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.