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Protein

D-alanine--D-alanine ligase

Gene

Caul_3404

Organism
Caulobacter sp. (strain K31)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Protein has several cofactor binding sites:
  • Mg2+SAAS annotation
  • Mn2+SAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseSAAS annotationImported
Biological processCell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciCSP366602:GH0Y-3428-MONOMER
UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
D-alanine--D-alanine ligaseSAAS annotation (EC:6.3.2.4SAAS annotation)
Gene namesi
Ordered Locus Names:Caul_3404Imported
OrganismiCaulobacter sp. (strain K31)Imported
Taxonomic identifieri366602 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
Proteomesi
  • UP000001316 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi366602.Caul_3404

Structurei

3D structure databases

ProteinModelPortaliB0T504
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini128 – 320ATP-graspInterPro annotationAdd BLAST193

Sequence similaritiesi

Belongs to the D-alanine--D-alanine ligase family.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105CPF Bacteria
COG1181 LUCA
HOGENOMiHOG000011592
KOiK01921
OMAiMQGLLEC
OrthoDBiPOG091H06GK

Family and domain databases

Gene3Di3.30.1490.20, 1 hit
InterProiView protein in InterPro
IPR011761 ATP-grasp
IPR013815 ATP_grasp_subdomain_1
IPR000291 D-Ala_lig_Van_CS
IPR011095 Dala_Dala_lig_C
IPR011127 Dala_Dala_lig_N
IPR016185 PreATP-grasp_dom_sf
PfamiView protein in Pfam
PF07478 Dala_Dala_lig_C, 1 hit
PF01820 Dala_Dala_lig_N, 1 hit
SUPFAMiSSF52440 SSF52440, 1 hit
PROSITEiView protein in PROSITE
PS50975 ATP_GRASP, 1 hit
PS00844 DALA_DALA_LIGASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

B0T504-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTTILFGGT SRERLVSVAS AKALATALPD ADLWFWAPDD KVYVASDAVL
60 70 80 90 100
QAHARPFEID LPTEGAAIGG IEAALDKAKA EERVLVLGMH GGAAENGDLA
110 120 130 140 150
ALCEARGVAF TGSDSRSSRL AFDKIATKAA VAKAGVVAPS TVELADAEAA
160 170 180 190 200
LAKYGKLVAK PVADGSSYGL IFVNGPADLE TLAAAAGREA YVIEPFVAGA
210 220 230 240 250
EATCGVLEQD GKVFALPPVE IRPADGAFDY VGKYLSKTTE EICPATFAPA
260 270 280 290 300
VNAAMQEAAL KAHKTVGAGG YSRSDFIVTP NGPIFLEINT LPGMTAASLY
310 320 330
PKSLKAQGIA FKDFLDGQIA LAVARAKAEA A
Length:331
Mass (Da):34,087
Last modified:April 8, 2008 - v1
Checksum:iBBB05B91C357B5A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000927 Genomic DNA Translation: ABZ72531.1
RefSeqiWP_012287428.1, NC_010338.1

Genome annotation databases

EnsemblBacteriaiABZ72531; ABZ72531; Caul_3404
KEGGicak:Caul_3404

Similar proteinsi

Entry informationi

Entry nameiB0T504_CAUSK
AccessioniPrimary (citable) accession number: B0T504
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: April 25, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health