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B0T504

- B0T504_CAUSK

UniProt

B0T504 - B0T504_CAUSK

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Protein
Submitted name:

D-alanine--D-alanine ligase

Gene

Caul_3404

Organism
Caulobacter sp. (strain K31)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Binds 2 magnesium or manganese ions per subunit.SAAS annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
  3. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciCSP366602:GH0Y-3435-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
Gene namesi
Ordered Locus Names:Caul_3404Imported
OrganismiCaulobacter sp. (strain K31)Imported
Taxonomic identifieri366602 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
ProteomesiUP000001316: Chromosome

Subcellular locationi

Cytoplasm SAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi366602.Caul_3404.

Structurei

3D structure databases

ProteinModelPortaliB0T504.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG1181.
HOGENOMiHOG000011592.
KOiK01921.
OMAiRITILFG.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0T504-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRTTILFGGT SRERLVSVAS AKALATALPD ADLWFWAPDD KVYVASDAVL
60 70 80 90 100
QAHARPFEID LPTEGAAIGG IEAALDKAKA EERVLVLGMH GGAAENGDLA
110 120 130 140 150
ALCEARGVAF TGSDSRSSRL AFDKIATKAA VAKAGVVAPS TVELADAEAA
160 170 180 190 200
LAKYGKLVAK PVADGSSYGL IFVNGPADLE TLAAAAGREA YVIEPFVAGA
210 220 230 240 250
EATCGVLEQD GKVFALPPVE IRPADGAFDY VGKYLSKTTE EICPATFAPA
260 270 280 290 300
VNAAMQEAAL KAHKTVGAGG YSRSDFIVTP NGPIFLEINT LPGMTAASLY
310 320 330
PKSLKAQGIA FKDFLDGQIA LAVARAKAEA A
Length:331
Mass (Da):34,087
Last modified:April 8, 2008 - v1
Checksum:iBBB05B91C357B5A0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000927 Genomic DNA. Translation: ABZ72531.1.
RefSeqiWP_012287428.1. NC_010338.1.
YP_001685029.1. NC_010338.1.

Genome annotation databases

EnsemblBacteriaiABZ72531; ABZ72531; Caul_3404.
GeneIDi5900859.
KEGGicak:Caul_3404.
PATRICi21319944. VBICauSp18104_3815.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000927 Genomic DNA. Translation: ABZ72531.1 .
RefSeqi WP_012287428.1. NC_010338.1.
YP_001685029.1. NC_010338.1.

3D structure databases

ProteinModelPortali B0T504.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 366602.Caul_3404.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABZ72531 ; ABZ72531 ; Caul_3404 .
GeneIDi 5900859.
KEGGi cak:Caul_3404.
PATRICi 21319944. VBICauSp18104_3815.

Phylogenomic databases

eggNOGi COG1181.
HOGENOMi HOG000011592.
KOi K01921.
OMAi RITILFG.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci CSP366602:GH0Y-3435-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K31Imported.

Entry informationi

Entry nameiB0T504_CAUSK
AccessioniPrimary (citable) accession number: B0T504
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 29, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3