B0T3J3 (CYSD_CAUSK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT

Gene names

Name:	cysD
Ordered Locus Names:	Caul_1750

Organism

Caulobacter sp. (strain K31) [Complete proteome] [HAMAP]

Taxonomic identifier

366602 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.
Sequence caution	The sequence ABZ70879.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 305	305	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_0000340191

Sequences

	Sequence		Length	Mass (Da)
	B0T3J3 [UniParc]. Last modified June 10, 2008. Version 2. Checksum: 0D00ED59784C0C1A	FASTA	305	35,010
	10 20 30 40 50 60 MSVLSPARLT HLQRLEAESI HILREVAAEC ENPVMLYSIG KDSAVMLHLA AKAFYPSRPP 70 80 90 100 110 120 FPLLHVDTTW KFRAMYELRD KVASDLGFDL LVHKNPEAEA RGINPFDHGS ALHTDLWKTE 130 140 150 160 170 180 GLKQALAKYG FDAAFGGARR DEEKSRAKER VFSFRTTEQR WDPKDQRPEL WKLYNTRKHP 190 200 210 220 230 240 GESLRVFPIS NWTELDVWQY IHLENIPIVP LYFAAERPVV ARDGSLIMVD DDRFRLRPGE 250 260 270 280 290 300 VPQMKSVRFR TLGCYPLTGA VESTAATLPQ VIQEMLLTTT SERQGRVIDH DQSASMEKKK QEGYF

References

[1]

"Complete sequence of chromosome of Caulobacter sp. K31." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Thompson L.S., Brettin T., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Kim E., Stephens C., Richardson P. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K31.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000927 Genomic DNA. Translation: ABZ70879.1. Different initiation.
RefSeq	YP_001683377.1. NC_010338.1.
3D structure databases
ProteinModelPortal	B0T3J3.
SMR	B0T3J3. Positions 8-215.
ModBase	Search...
Protein-protein interaction databases
STRING	B0T3J3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5899205.
GenomeReviews	Gene locus Caul_1750 in contig CP000927_GR.
KEGG	cak:Caul_1750.
PATRIC	21316536. VBICauSp18104_2128.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG758022.
ProtClustDB	PRK05253.
Enzyme and pathway databases
BioCyc	CSP78:CAUL_1750-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_CAUSK

Accession

Primary (citable) accession number: B0T3J3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program