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B0T2Y6

- G6PI_CAUSK

UniProt

B0T2Y6 - G6PI_CAUSK

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Caulobacter sp. (strain K31)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei349 – 3491Proton donorUniRule annotation
    Active sitei380 – 3801UniRule annotation
    Active sitei508 – 5081UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciCSP366602:GH0Y-4740-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:Caul_4688
    OrganismiCaulobacter sp. (strain K31)
    Taxonomic identifieri366602 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
    ProteomesiUP000001316: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 539539Glucose-6-phosphate isomerasePRO_1000081233Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi366602.Caul_4688.

    Structurei

    3D structure databases

    ProteinModelPortaliB0T2Y6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261370.
    KOiK01810.
    OMAiRAHYVSN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0T2Y6-1 [UniParc]FASTAAdd to Basket

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    MADLAAAWTR LEAAAKVAGE KRIALMFEAE PGRLAALTLN VAGLHIDLSK    50
    QAWDEAGLEA ALDLAHAADV EGARTRMFGG EAINSSEGRA VLHTALRAAK 100
    DADVRAGGVP VMAEVEAVRV RMKAFTEAVR SGAIKGATGK PFKAILHIGI 150
    GGSDLGPRLL WDALRPIKPT IDLRFVANVD GAEFALTTAD LDPAETLVIV 200
    VSKTFTTQET LANAAAARAW LSAALGEQGA NQHLAAISTA LDKTAAFGVA 250
    DDRVFGFWDW VGGRYSLWSS VSLSVAVACG WEAFEGFLQG GAAMDAHFRD 300
    APLEKNAAVL IALAQIFNRN GLDRRARSVV PYSHRLRRLA SFLQQLEMES 350
    NGKSVGPDGQ AVKHGTATVV FGDEGANVQH AYFQCMHQGT DITPLEFVAL 400
    AQSDEGPAGM HAKLLSNVLA QAEALMVGRT IEDVRTELVA KGVSEAEIAT 450
    LAPQRAFAGN RPSTMVVLDR LTPQTFGALI ALYEHKTFVE GVIWGVNSFD 500
    QWGVELGKVM AGRILPELES GAAGRHDPST AALIERLKL 539
    Length:539
    Mass (Da):57,254
    Last modified:April 8, 2008 - v1
    Checksum:i0EE18B19E024031D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000927 Genomic DNA. Translation: ABZ73808.1.
    RefSeqiWP_012288681.1. NC_010338.1.
    YP_001686306.1. NC_010338.1.

    Genome annotation databases

    EnsemblBacteriaiABZ73808; ABZ73808; Caul_4688.
    GeneIDi5902150.
    KEGGicak:Caul_4688.
    PATRICi21322554. VBICauSp18104_5100.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000927 Genomic DNA. Translation: ABZ73808.1 .
    RefSeqi WP_012288681.1. NC_010338.1.
    YP_001686306.1. NC_010338.1.

    3D structure databases

    ProteinModelPortali B0T2Y6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 366602.Caul_4688.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABZ73808 ; ABZ73808 ; Caul_4688 .
    GeneIDi 5902150.
    KEGGi cak:Caul_4688.
    PATRICi 21322554. VBICauSp18104_5100.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261370.
    KOi K01810.
    OMAi RAHYVSN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci CSP366602:GH0Y-4740-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K31.

    Entry informationi

    Entry nameiG6PI_CAUSK
    AccessioniPrimary (citable) accession number: B0T2Y6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3