SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B0T162

- TRMB_CAUSK

UniProt

B0T162 - TRMB_CAUSK

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, Caul_0028
Organism
Caulobacter sp. (strain K31)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei59 – 591S-adenosyl-L-methionine By similarity
Binding sitei84 – 841S-adenosyl-L-methionine By similarity
Binding sitei111 – 1111S-adenosyl-L-methionine By similarity
Active sitei133 – 1331 By similarity
Binding sitei133 – 1331S-adenosyl-L-methionine By similarity
Binding sitei137 – 1371Substrate By similarity
Binding sitei169 – 1691Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciCSP366602:GH0Y-28-MONOMER.
    UniPathwayiUPA00989.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
    Alternative name(s):
    tRNA (guanine(46)-N(7))-methyltransferase
    tRNA(m7G46)-methyltransferase
    Gene namesi
    Name:trmB
    Ordered Locus Names:Caul_0028
    OrganismiCaulobacter sp. (strain K31)
    Taxonomic identifieri366602 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
    ProteomesiUP000001316: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 226226tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
    PRO_1000084437Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi366602.Caul_0028.

    Structurei

    3D structure databases

    ProteinModelPortaliB0T162.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni139 – 1446Interaction with RNA Reviewed prediction
    Regioni206 – 2094Substrate binding By similarity

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0220.
    HOGENOMiHOG000073969.
    KOiK03439.
    OMAiGRNFREN.
    OrthoDBiEOG6K6VBC.

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    HAMAPiMF_01057. tRNA_methyltr_TrmB.
    InterProiIPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view]
    PfamiPF02390. Methyltransf_4. 1 hit.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 1 hit.
    TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
    PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0T162-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTHPQQPHGP LRSFGRLKSR PVKPRQQALL DTLLPQIAVP TAPFQPRDLM    50
    PEAQEVWLEI GFGGGEHMAA QAGKRPDVLM IGAEPFVNGV ASAVRHVEEQ 100
    ALKNVRIHEG DARDVVGWLP DASIDRLFIM FPDPWHKARH NKRRLVQPAF 150
    VAELARVLKP GAGFRFATDW ADYAQWTVER VLADPAFRFA DAEAVRNAPP 200
    ADHVTTRYEE KKLGDCAPVF LDFVRI 226
    Length:226
    Mass (Da):25,360
    Last modified:April 8, 2008 - v1
    Checksum:iA5F8BF67AFEE04D3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000927 Genomic DNA. Translation: ABZ69166.1.
    RefSeqiWP_012284124.1. NC_010338.1.
    YP_001681664.1. NC_010338.1.

    Genome annotation databases

    EnsemblBacteriaiABZ69166; ABZ69166; Caul_0028.
    GeneIDi5897740.
    KEGGicak:Caul_0028.
    PATRICi21313062. VBICauSp18104_0406.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000927 Genomic DNA. Translation: ABZ69166.1 .
    RefSeqi WP_012284124.1. NC_010338.1.
    YP_001681664.1. NC_010338.1.

    3D structure databases

    ProteinModelPortali B0T162.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 366602.Caul_0028.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABZ69166 ; ABZ69166 ; Caul_0028 .
    GeneIDi 5897740.
    KEGGi cak:Caul_0028.
    PATRICi 21313062. VBICauSp18104_0406.

    Phylogenomic databases

    eggNOGi COG0220.
    HOGENOMi HOG000073969.
    KOi K03439.
    OMAi GRNFREN.
    OrthoDBi EOG6K6VBC.

    Enzyme and pathway databases

    UniPathwayi UPA00989 .
    BioCyci CSP366602:GH0Y-28-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    HAMAPi MF_01057. tRNA_methyltr_TrmB.
    InterProi IPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view ]
    Pfami PF02390. Methyltransf_4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 1 hit.
    TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
    PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K31.

    Entry informationi

    Entry nameiTRMB_CAUSK
    AccessioniPrimary (citable) accession number: B0T162
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: April 8, 2008
    Last modified: September 3, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

    Similar proteinsi