B0T091 (B0T091_CAUSK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase 1 HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2-1 HAMAP MF_01902
Ordered Locus Names:	Caul_4461

Organism

Caulobacter sp. (strain K31) [Complete proteome] [HAMAP]

Taxonomic identifier

366602 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter

Protein attributes

Sequence length	1117 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0T091 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 881F790210D65DEA	FASTA	1,117	124,275
	10 20 30 40 50 60 MKTHAYAELQ ATTNFSFLRG ASHAQELMLT GQALGLTAVG VADRNSLAGV VRAWTAAKDL 70 80 90 100 110 120 KIRALTGCRL DFMDGAPSLL CYPSDREAFG RLTRLLTVGQ RRAGKGECHL SWKDFLEHAE 130 140 150 160 170 180 GQLALIVPPA RLDEAFEADL ARIAGELRGR VWLAASRAYA AQDLKRLSRL ADLAREARAP 190 200 210 220 230 240 MVATNDVLYH GPERRPLQDV MTCIREGCTI TQAGFRLEAN AERHIKTPAE MARLFERWPQ 250 260 270 280 290 300 AVERTIEIVE RIGFDLGDLK EQYPDEPVPP GKTAMQHLTD LTWQGAAWRY PNGVSPKVAD 310 320 330 340 350 360 QLREELRLIA KMDYPNYFIT VHDIVHKARE MGILCQGRGS AANSSVCFCL GVTAIDPTEH 370 380 390 400 410 420 RLLFTRFISE NRGEPPDIDV DFEHERREEV MQYVYKRYGR EYAAICCTVI HYRPRSAIRD 430 440 450 460 470 480 VGKALGLTED ITAILANTVW GSWGDGLPDE HIKQTGLDPN NPQIARAIAL ATELLQHPRH 490 500 510 520 530 540 LSQHVGGFVL TKRRLDETVP IGNAAMKDRT FIEWDKDDID SLKLMKVDIL ALGMLTAIQR 550 560 570 580 590 600 AFGMLRADHG QPITDLADVP VEVKGVYDML SVADSVGVFQ VESRAQMSML PRLKPNKFYD 610 620 630 640 650 660 LVIEVAIVRP GPIQGDMVHP YLRRRQGLEK AEWPAPSPEH GHKDELREIL GNTFGVPLFQ 670 680 690 700 710 720 EQAMSLAIEA AKFTPDEADG LRKAMATFKN LGDPGEYRDK FVEGMVRRGY ERDFATRCFK 730 740 750 760 770 780 QIEGFGSYGF PESHAASFAK LVYISAWIKW AWPDVFCAAL INSQPMGFYQ PAQLVRDARE 790 800 810 820 830 840 HGVEVRAPDV LMSDWDCTLE GVSIAQTSTV IPDEAQRRSG TDPERRVSGG PGSSRSALVR 850 860 870 880 890 900 DDRAFQPASD KLFNPDTRPF WKAVRLGLRQ IKGLKEDDAK LIEEVRAEGA RTPADFARAG 910 920 930 940 950 960 VSQRGLELLA EADAFASAGL TRRDALWAVK GLKGEAKVDS QAPLLAGLPL FDTAVALPTM 970 980 990 1000 1010 1020 ALPQQVAEDY RTTSLSLKAH PLRFFRPMLD QLNVTPAERL KGVRNGRKVS VGGLVLIRQR 1030 1040 1050 1060 1070 1080 PGTAKGVVFL TLEDETGVAN AVVWKDCFDA HRRTVMSASF LIVHGKLQAS EGVIHVVAER 1090 1100 1110 FTDLSAELAR LRESPEAPTP TVRMRTSGRL QRSRDFH

References

[1]

"Complete sequence of chromosome of Caulobacter sp. K31." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Thompson L.S., Brettin T., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Kim E., Stephens C., Richardson P. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K31.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000927 Genomic DNA. Translation: ABZ73581.1.
RefSeq	YP_001686079.1. NC_010338.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B0T091.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5901922.
GenomeReviews	Gene locus Caul_4461 in contig CP000927_GR.
KEGG	cak:Caul_4461.
PATRIC	21322102. VBICauSp18104_4874.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	LATNRNG.
ProtClustDB	CLSK891351.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0T091_CAUSK

Accession

Primary (citable) accession number: B0T091

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)