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B0T019 (SYR_CAUSK) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Caul_4389
OrganismCaulobacter sp. (strain K31) [Complete proteome] [HAMAP]
Taxonomic identifier366602 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter

Protein attributes

Sequence length613 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 613613Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000076207

Regions

Motif123 – 13311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B0T019 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 5B3EFD61B385698C

FASTA61367,521
        10         20         30         40         50         60 
MSDLKRSLSE AAAAAFQAAG LSPDFGRVTA SDRPDLADFQ CNGALAAAKS AKRNPREIAV 

        70         80         90        100        110        120 
QVVDVLKADP RLASVEIAGV GFINMRVSTD ALSIRANEIA ADPRAGAEPL AHPRRVLVDY 

       130        140        150        160        170        180 
AGPNVAKPMH VGHLRASIIG ESVKRLYRFR GDDVVGDAHF GDWGFQMGLL ISAIMEEDAF 

       190        200        210        220        230        240 
IRALLERLVE APREFSKADE DKVMSEFAQR VTLDDLDRLY PAASARQKED PEFKEKARKA 

       250        260        270        280        290        300 
TAELQNGRFG YRLLWRHFVN ISRVALEREF HALGVDFDLW KGESDVQDLI APMVRQLEVK 

       310        320        330        340        350        360 
GLLVDDQGAR IVRVARPGET KKKKLPDGSV VEVESPDPLL VVSSEGSAMY GTTDLATILD 

       370        380        390        400        410        420 
RRKSFDPHLI LYCVDQRQAD HFEQVFRAAY LAGYAEPGSL EHIGFGTMNG SDGKPFKTRA 

       430        440        450        460        470        480 
GGVLKLHDLI EMAREKARER LREAGLGAEL SQEAFEETAH KVGIAALKFA DLQNFRGTSY 

       490        500        510        520        530        540 
VFDLDRFTSF EGKTGPYLLY QSVRIKSILR KAAEQKVVSG AIIVGEPAER DLTLLLDAFE 

       550        560        570        580        590        600 
GALSEAYDKK APNFIAEHAY KLAQTFSKFY AACPILSADN DATRASRLAL AETTLKQLEL 

       610 
ALDLLGIEAP ERM 

« Hide

References

[1]"Complete sequence of chromosome of Caulobacter sp. K31."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Thompson L.S., Brettin T., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Kim E., Stephens C., Richardson P.
Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K31.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000927 Genomic DNA. Translation: ABZ73509.1.
RefSeqYP_001686007.1. NC_010338.1.

3D structure databases

ProteinModelPortalB0T019.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING366602.Caul_4389.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABZ73509; ABZ73509; Caul_4389.
GeneID5901850.
KEGGcak:Caul_4389.
PATRIC21321946. VBICauSp18104_4797.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMAHDVERIS.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycCSP366602:GH0Y-4439-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_CAUSK
AccessionPrimary (citable) accession number: B0T019
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: May 14, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries