B0SZ07 (B0SZ07_CAUSK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ABZ71918.1
EC=2.4.1.182 EMBL ABZ71918.1

Gene names

Ordered Locus Names:

Caul_2791

Organism

Caulobacter sp. (strain K31) [Complete proteome] [HAMAP]

Taxonomic identifier

366602 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ABZ71918.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0SZ07 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 30D8A7F340839FB1	FASTA	399	42,210
	10 20 30 40 50 60 MSPESLSKSG PLTVMLVAAE ASGDVLGAGL ARALRGRLGA DKVRFVGVGG ARMALEGVDS 70 80 90 100 110 120 PFDIAQLSIL GLLESLKAYP RAMARLKDTL ALAAREKPDV AVLIDSWGFN IRLAKALRKQ 130 140 150 160 170 180 DPGLPLVKYV APQVWAYRAG RAKDLAGAVD LLLSIQPMDR SFFDAVDLPN VFVGNSALAH 190 200 210 220 230 240 DFSHADPARL RAAIGAGPGD PILLVLPGSR PSEIERVMPR FEEAVTRLKV RRPDLHVVVP 250 260 270 280 290 300 AASTVAQSVK ARVAAWPFRA HVVEDDVLKD DAMVAGTVAL ACSGTVTTEL ALAGCPMVVG 310 320 330 340 350 360 YVTANLTYAL LKMMFKQRWV TLFNIAAQDT VAPELLQDAC TGEALAAEVA LRLDDPDLRA 370 380 390 RQIAAQNAAL DRMGRGMPDP SEAAATALLT CLGARGLAV

References

[1]

"Complete sequence of chromosome of Caulobacter sp. K31." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Bruce D., Goodwin L., Thompson L.S., Brettin T., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Kim E., Stephens C., Richardson P. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K31.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000927 Genomic DNA. Translation: ABZ71918.1.
RefSeq	YP_001684416.1. NC_010338.1.
3D structure databases
ProteinModelPortal	B0SZ07.
ModBase	Search...
Protein-protein interaction databases
STRING	B0SZ07.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5900246.
GenomeReviews	Gene locus Caul_2791 in contig CP000927_GR.
KEGG	cak:Caul_2791.
PATRIC	21318658. VBICauSp18104_3186.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	PDFNLGL.
ProtClustDB	CLSK890663.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0SZ07_CAUSK

Accession

Primary (citable) accession number: B0SZ07

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)