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B0SSV1 (SYR_LEPBP) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:LEPBI_I2089
OrganismLeptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris) [Complete proteome] [HAMAP]
Taxonomic identifier456481 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira

Protein attributes

Sequence length594 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 594594Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000198915

Regions

Motif133 – 14311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B0SSV1 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: D11E0BDE79BB4F6C

FASTA59468,753
        10         20         30         40         50         60 
MKANQLLKNL VLTELESAVS SYLTKQKIDL PLTEFKIRIE YSRDEKFGDY SSPFALENKN 

        70         80         90        100        110        120 
ILKLNPKEIA EGVLSEIKNE TLFEFVTFSP PGFINFRIRS QFLIQYTNQV MSPMVTFAKT 

       130        140        150        160        170        180 
DEKQSILLEF VSANPTGPMN IVSARSAAYG DALANLLLSL GHTVKREFYV NDYGNQVYLL 

       190        200        210        220        230        240 
GVAVLLRIFE EKGEKISFQE DESKESVFTL IEKRILPKES YRGEYIRDIA KEVLSNKTKS 

       250        260        270        280        290        300 
IQVEEWIQNK NWDECIHDLS KYAVEYNLSR QKEDLKLFGV HFDQFFSERS LHEAGDVENV 

       310        320        330        340        350        360 
PTLLKKEDVS TIDGKLHFLS TQYGDDKDRV IRREDGRPTY LMADIAYHFD KYKRGFTKLI 

       370        380        390        400        410        420 
DIWGPDHYGY IARLKGAVLS FGKSNDSFLI LIAQQVNLIE NKEKVKMSKR LGIFQTMRDL 

       430        440        450        460        470        480 
LSYLGKNGKD VGRYFFLMRS SDAPLDFDLD LAKDESDKNP VFYIQYAHAR ICSIFRELQI 

       490        500        510        520        530        540 
SIADWSIPKV VSGDCFQSEE RLRLLFWVAR FQEEVYDTAT NLEPHRLTNY LQSLSKAFTK 

       550        560        570        580        590 
FYSHKDNRIK EKQGEEREQL LFLILFTKRA IASGLELLGI SSPEKMSKED ESNT 

« Hide

References

[1]"Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis."
Picardeau M., Bulach D.M., Bouchier C., Zuerner R.L., Zidane N., Wilson P.J., Creno S., Kuczek E.S., Bommezzadri S., Davis J.C., McGrath A., Johnson M.J., Boursaux-Eude C., Seemann T., Rouy Z., Coppel R.L., Rood J.I., Lajus A. expand/collapse author list , Davies J.K., Medigue C., Adler B.
PLoS ONE 3:E1607-E1607(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Patoc 1 / ATCC 23582 / Paris.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000786 Genomic DNA. Translation: ABZ98191.1.
RefSeqYP_001839467.1. NC_010602.1.

3D structure databases

ProteinModelPortalB0SSV1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING456481.LEPBI_I2089.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABZ98191; ABZ98191; LEPBI_I2089.
GeneID6222601.
KEGGlbi:LEPBI_I2089.
PATRIC22351016. VBILepBif123590_2134.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMALCNVLAK.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycLBIF456481:GCM0-2076-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_LEPBP
AccessionPrimary (citable) accession number: B0SSV1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 8, 2008
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries