B0SJA9 (ENGB_LEPBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable GTP-binding protein EngB

Gene names

Name:	engB
Ordered Locus Names:	LEPBI_I0562

Organism

Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris) [Complete proteome] [HAMAP]

Taxonomic identifier

456481 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Leptospiraceae › Leptospira

Protein attributes

Sequence length	213 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Necessary for normal cell division and for the maintenance of normal septation By similarity. HAMAP MF_00321
Sequence similarities	Belongs to the EngB family. Contains 1 G (guanine nucleotide-binding) domain.

Ontologies

Keywords
Biological process	Cell cycle Cell division Septation
Ligand	GTP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	barrier septum assembly Inferred from electronic annotation. Source: UniProtKB-KW cell cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 213	213	Probable GTP-binding protein EngB HAMAP MF_00321		PRO_1000189927
Regions
	Domain	43 – 148	106	G
	Nucleotide binding	38 – 45	8	GTP Potential
	Nucleotide binding	83 – 87	5	GTP Potential
	Nucleotide binding	150 – 153	4	GTP Potential

Sequences

	Sequence		Length	Mass (Da)
	B0SJA9 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: C90A00D5DAB8300B	FASTA	213	24,110
	10 20 30 40 50 60 MHKYSKEIPF PETKFFTSIA KLDEKEDLDS VQSIAFMGRS NSGKSSLLNA LSNHRGLAKV 70 80 90 100 110 120 SRTPGKTKLI NIFRTKVGFN LVDLPGFGYS KASHKEHKDM MNLLEGFLNS WKQLKILFIL 130 140 150 160 170 180 CDSQRDFPEE ELSTIEVAME KKIKPVVIRT KIDKLNQSGQ HKVRTEMEAA MNEIGIPFRV 190 200 210 FYISASTGRG IGELREFILE TLGIQTKVSN VEP

References

[1]

"Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis." Picardeau M., Bulach D.M., Bouchier C., Zuerner R.L., Zidane N., Wilson P.J., Creno S., Kuczek E.S., Bommezzadri S., Davis J.C., McGrath A., Johnson M.J., Boursaux-Eude C., Seemann T., Rouy Z., Coppel R.L., Rood J.I., Lajus A. , Davies J.K., Medigue C., Adler B. PLoS ONE 3:E1607-E1607(2008) [PubMed: 18270594] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Patoc 1 / ATCC 23582 / Paris.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000786 Genomic DNA. Translation: ABZ96700.1.
RefSeq	YP_001837976.1. NC_010602.1.
3D structure databases
ProteinModelPortal	B0SJA9.
ModBase	Search...
Protein-protein interaction databases
STRING	B0SJA9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6221495.
GenomeReviews	Gene locus LEPBI_I0562 in contig CP000786_GR.
KEGG	lbi:LEPBI_I0562.
PATRIC	22347828. VBILepBif123590_0564.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG447097.
OMA	TITLNYY.
ProtClustDB	PRK00454.
Enzyme and pathway databases
BioCyc	LBIF456481:LEPBI_I0562-MONOMER.
Family and domain databases
HAMAP	MF_00321. GTPase_EngB. [Tree]
InterPro	IPR019987. GTP-bd_ribosome_bio_YsxC. IPR006073. GTP_binding_domain. [Graphical view]
KO	K03978.
Pfam	PF01926. MMR_HSR1. 1 hit. [Graphical view]
TIGRFAMs	TIGR03598. GTPase_YsxC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ENGB_LEPBP

Accession

Primary (citable) accession number: B0SJA9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	April 8, 2008
Last modified:	January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program