B0SHF6 (B0SHF6_LEPBA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Bifunctional dihydrolipoyllysine-residue acetyltransferase/dihydrolipoyllysine-residue succinyltransferase EMBL ABZ94017.1

Gene names

Name:	acoC EMBL ABZ94017.1
Ordered Locus Names:	LBF_1505

Organism

Leptospira biflexa serovar Patoc (strain Patoc 1 / Ames) [Complete proteome] [HAMAP]

Taxonomic identifier

355278 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Leptospiraceae › Leptospira

Protein attributes

Sequence length	463 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423

Ontologies

Keywords
Domain	Lipoyl RuleBase RU003765 SAAS SAAS003016
Molecular function	Acyltransferase RuleBase RU003765 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	pyruvate dehydrogenase complex Inferred from electronic annotation. Source: InterPro
Molecular function	dihydrolipoyllysine-residue acetyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0SHF6 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 7CCD33C7772BBF90	FASTA	463	49,752
	10 20 30 40 50 60 MAKIQEMTQL SPTMEEGTIV KWLKNEGDAI SPGDILAEVE TDKAVMEMEA YDAGVILKII 70 80 90 100 110 120 QQEGTKLRVG EAMAIIGKPG EDISSLLSNL PKKETQAKGP NPTSPSPSGE VSSESGANGN 130 140 150 160 170 180 DRAITQEKAI QEKQTLETPT EAQFPVAQGS AIPTKNSSSS QKPLPLSNIP RGSLRVLASP 190 200 210 220 230 240 LAKSIAIEHG IDLHQVLGTG PEGRITKKDV LDSLNKGFRP SSFDSDKMSQ DEVVSLNGMR 250 260 270 280 290 300 KTIAKRLTES KQNLPHFYLN VDINAKALES FRKEINDFQT SQNPDSANKV SLNDIIVKAT 310 320 330 340 350 360 AAALKLHPKV NASFQGDSIL QFGRVDVGIA VSIDGGLLTP VIRDANRKSI LEISKEVKEL 370 380 390 400 410 420 AKKARDRKLK PEEFTNGTFT ISNLGMYGIS RFTAIINEPE GAILAVGSAE DKPVVENGVV 430 440 450 460 VAGRVISLTL SCDHRVIDGA VGAEFLKTLR SFLEKPNLLL AVG

References

[1]

"Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis." Picardeau M., Bulach D.M., Bouchier C., Zuerner R.L., Zidane N., Wilson P.J., Creno S., Kuczek E.S., Bommezzadri S., Davis J.C., McGrath A., Johnson M.J., Boursaux-Eude C., Seemann T., Rouy Z., Coppel R.L., Rood J.I., Lajus A. , Davies J.K., Medigue C., Adler B. PLoS ONE 3:E1607-E1607(2008) [PubMed: 18270594] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000777 Genomic DNA. Translation: ABZ94017.1.
RefSeq	YP_001962595.1. NC_010842.1.
3D structure databases
ProteinModelPortal	B0SHF6.
ModBase	Search...
Protein-protein interaction databases
STRING	B0SHF6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6389608.
GenomeReviews	Gene locus LBF_1505 in contig CP000777_GR.
KEGG	lbf:LBF_1505.
PATRIC	22342081. VBILepBif95142_1600.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG630916.
OMA	HGRIIKQ.
ProtClustDB	CLSK574149.
Family and domain databases
InterPro	IPR003016. 2-oxoA_DH_lipoyl-BS. IPR001078. 2-oxoacid_DH_actylTfrase. IPR006257. AcTrfase_Pyrv_DH_cplx_L. IPR000089. Biotin_lipoyl. IPR023213. CAT-like_dom. IPR004167. E3-bd. IPR011053. Single_hybrid_motif. [Graphical view]
Gene3D	G3DSA:3.30.559.10. CAT-like_dom. 1 hit. G3DSA:4.10.320.10. E3_bd. 1 hit.
KO	K00627.
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00364. Biotin_lipoyl. 1 hit. PF02817. E3_binding. 1 hit. [Graphical view]
SUPFAM	SSF47005. E3_bd. 1 hit. SSF51230. Hybrid_motif. 1 hit.
TIGRFAMs	TIGR01349. PDHac_trf_mito. 1 hit.
PROSITE	PS50968. BIOTINYL_LIPOYL. 1 hit. PS00189. LIPOYL. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B0SHF6_LEPBA

Accession

Primary (citable) accession number: B0SHF6

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)