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Protein
Submitted name:

Signal transduction protein with multiple domains

Gene

LBF_2565

Organism
Leptospira biflexa serovar Patoc (strain Patoc 1 / Ames)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciLBIF355278:GHTJ-2561-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Signal transduction protein with multiple domainsImported
Gene namesi
Ordered Locus Names:LBF_2565Imported
OrganismiLeptospira biflexa serovar Patoc (strain Patoc 1 / Ames)Imported
Taxonomic identifieri355278 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000001846 Componenti: Chromosome I

Interactioni

Protein-protein interaction databases

STRINGi355278.LBF_2565.

Structurei

3D structure databases

ProteinModelPortaliB0SE18.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0515.
OMAiLLMIEYS.
OrthoDBiEOG6HTNS7.

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
3.30.450.40. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003018. GAF.
IPR029016. GAF_dom_like.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR001932. PP2C-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF00069. Pkinase. 1 hit.
PF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTiSM00065. GAF. 1 hit.
SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0SE18-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFTIGKYKVI KELHLGKRSS VYIGEDEKKS QVVIKLLNRD YPDNHEITRF
60 70 80 90 100
KNEYEILKSI DSPYTLKPLG FESYQNSVAI VFPHIEYSDL AQLQLSGKYS
110 120 130 140 150
NLQTFLNISI EICKALSDIH KAKVVHNDIK AQNIIYHPET GKLKIIDFGS
160 170 180 190 200
ATLLTHRSFY LPMNQNLTGT LAHISPEQTG RMNRTVDYRT DFYSLGITLY
210 220 230 240 250
QLITGELPFL YTDSLEMVHA HLARIPLSPK ERSHTPIILS DLIMKLLEKN
260 270 280 290 300
PEDRYQTATG LLSDLITIQS VLLENGKEAL DSFKIELAKN DKSSRFQIPK
310 320 330 340 350
KLYGRETQLQ TFEEKFLNAT EGKIEIFLIS GRSGIGKSAL INEIQKPVTI
360 370 380 390 400
ERAYFTSGKF DLYKKSIPYR AINLALQSLV KQLLSESETA VKEWKTTLTK
410 420 430 440 450
TLGTNAKLII DVVPELAQLL GEVSIPPELD TVEMENRFHL VFRKFLRTVC
460 470 480 490 500
TKEHPVVMFL DDLQWADSSS ILLLKEVVTD PEISYFFAIL SYRDNEVSPT
510 520 530 540 550
DPIFRMLEEL RESKTSITEI RLEPLIESDI SLLVSETLSL PEPEIKGISE
560 570 580 590 600
IIWKKTKGNP FHVNEMFKNL YERSYIQFLE NRWVWDKEKI DAVNISENVI
610 620 630 640 650
DLIIDKINLQ PPNLVETLKL TACIGNWFRH DIYATIAERP FHLASMDLVA
660 670 680 690 700
LANEEFLILG LEDANFTHDK IREAIYKIIS PEEKSKLHYK IGKTYLSILY
710 720 730 740 750
KYKLDDHLFT IVNQLNLGAS QITKEQELVQ LRTLNERAGF KALNSSAYDA
760 770 780 790 800
AFIFFERMVG LMNDDEWISQ YDNTLKLHLA YARSAYLSKN FEKAEKSFNY
810 820 830 840 850
ILKNAKTDLE KILVYELQSS MLVTQNKMKE VLVTLKQALK LLGVRLPKNA
860 870 880 890 900
STLSPLKEII KFKLRLGRKP IEELEFLPVT TEPKYLAIMR LLNACIAPSF
910 920 930 940 950
LAEPNLFPVI VLKMVNYSLV NGLCELSAFG FCAMGMIQGS GLGDYETGLK
960 970 980 990 1000
FGKLGVKLLD LFESKTFKCR TIFMYTCMIS PWKNHAREGK NLFWESFLIG
1010 1020 1030 1040 1050
METGDLQYAS YSLNNIHFQG LMYRENLDDL YKSQLRYDAS LLSLRQHHAY
1060 1070 1080 1090 1100
QVHRLNMQIV ENMRGESSDP LSLEGRYFLE SEIVKEWESA ENSNALFDYY
1110 1120 1130 1140 1150
LCKLRLEYFL GDIQKAYQAS LKLDGLEGAV FGMMFVPEHV FFGALVVYEL
1160 1170 1180 1190 1200
LSNQTESIGI PKQSLVKRLK NFSKRLKVWA GNSPDNFGHK YEIVSAIELY
1210 1220 1230 1240 1250
ISNKKSDAVI ACKAAITSAR ESGYILEEAI ANEILVRMWK ETGFDQYSNL
1260 1270 1280 1290 1300
HLVEAHYRYG KYGFISKVKQ LETQHISLKK YIGRNFRTDS TDNVSLFSTT
1310 1320 1330 1340 1350
KDIFGDVGSN LDINTVIKAS QTISGEIQLN RLLEKMMKII LENAGAERGY
1360 1370 1380 1390 1400
FILNLESKWQ VIAESNLETE SVSVYSDSPF ELDFSQEITS INQNKIPAQI
1410 1420 1430 1440 1450
IGYVIRTGVV VICGDAAREG EFKNDPYVKA FLPKSLLCYP ILSHGTVVGI
1460 1470 1480 1490 1500
VYLENNLTTD AFTPGRVEIL KILSSQIAVS IENSLLYSNL EQKVDERTKE
1510 1520 1530 1540 1550
LNSALTEVKG LKEQQDGDYF LASLLIEPLT QNHAKSSNMN IQFLTEQKKK
1560 1570 1580 1590 1600
FSYKQWNSEI GGDLCVSSSI QLQNKKYIVV LNGDAMGKSM QGASGALVIG
1610 1620 1630 1640 1650
SVFEAIIKRN GQSEETRDIT PERWVSNAYF ELHNTLVTFD GSMLIPMFLC
1660 1670 1680 1690 1700
LIDDETGFFY FLNAEHPRPV LYRNGKTFFL PHNYVCAKLG LLASKKSLQI
1710 1720 1730 1740 1750
NTFQMEKGDI LLIGSDGRDD ILIGSEVEME VNEDDELFLK TALAGMGELN
1760 1770 1780 1790 1800
LIRDAIKRHG ELIDDLSLIR VEYTGLGSEI NIPKSHPKHI VYLRALTLYK
1810 1820 1830 1840 1850
QKLWSDVEKM ISANFPDIND APLSFQKIYL YTEHRMSVFP LQFAVSYVQK
1860 1870 1880 1890 1900
NPSDSLTLFY IAEALFSNGD YGAAFDYSER VKLRRPYHKE NNRLFARLTA

LRRNSI
Length:1,906
Mass (Da):217,619
Last modified:April 8, 2008 - v1
Checksum:iA94B6E6C70101925
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000777 Genomic DNA. Translation: ABZ95049.1.
RefSeqiYP_001963627.1. NC_010842.1.

Genome annotation databases

EnsemblBacteriaiABZ95049; ABZ95049; LBF_2565.
KEGGilbf:LBF_2565.
PATRICi22344269. VBILepBif95142_2679.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000777 Genomic DNA. Translation: ABZ95049.1.
RefSeqiYP_001963627.1. NC_010842.1.

3D structure databases

ProteinModelPortaliB0SE18.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi355278.LBF_2565.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABZ95049; ABZ95049; LBF_2565.
KEGGilbf:LBF_2565.
PATRICi22344269. VBILepBif95142_2679.

Phylogenomic databases

eggNOGiCOG0515.
OMAiLLMIEYS.
OrthoDBiEOG6HTNS7.

Enzyme and pathway databases

BioCyciLBIF355278:GHTJ-2561-MONOMER.

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
3.30.450.40. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003018. GAF.
IPR029016. GAF_dom_like.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR001932. PP2C-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF00069. Pkinase. 1 hit.
PF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTiSM00065. GAF. 1 hit.
SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis."
    Picardeau M., Bulach D.M., Bouchier C., Zuerner R.L., Zidane N., Wilson P.J., Creno S., Kuczek E.S., Bommezzadri S., Davis J.C., McGrath A., Johnson M.J., Boursaux-Eude C., Seemann T., Rouy Z., Coppel R.L., Rood J.I., Lajus A.
    , Davies J.K., Medigue C., Adler B.
    PLoS ONE 3:E1607-E1607(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Patoc 1 / AmesImported.

Entry informationi

Entry nameiB0SE18_LEPBA
AccessioniPrimary (citable) accession number: B0SE18
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: April 29, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.