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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Leptospira biflexa serovar Patoc (strain Patoc 1 / Ames)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:LBF_2035
OrganismiLeptospira biflexa serovar Patoc (strain Patoc 1 / Ames)
Taxonomic identifieri355278 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001989141 – 594Arginine--tRNA ligaseAdd BLAST594

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB0SB29.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi133 – 143"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247214.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.

Sequencei

Sequence statusi: Complete.

B0SB29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKANQLLKNL VLTELESAVS SYLTKQKIDL PLTEFKIRIE YSRDEKFGDY
60 70 80 90 100
SSPFALENKN ILKLNPKEIA EGVLSEIKNE TLFEFVTFSP PGFINFRIRS
110 120 130 140 150
QFLIQYTNQV MSPMVTFAKT DEKQSILLEF VSANPTGPMN IVSARSAAYG
160 170 180 190 200
DALANLLLSL GHTVKREFYV NDYGNQVYLL GVAVLLRIFE EKGEKISFQE
210 220 230 240 250
DESKESVFTL IEKRILPKES YRGEYIRDIA KEVLSNKTKS IQVEEWIQNK
260 270 280 290 300
NWDECIHDLS KYAVEYNLSR QKEDLKLFGV HFDQFFSERS LHEAGDVENV
310 320 330 340 350
PTLLKKEDVS TIDGKLHFLS TQYGDDKDRV IRREDGRPTY LMADIAYHFD
360 370 380 390 400
KYKRGFTKLI DIWGPDHYGY IARLKGAVLS FGKSNDSFLI LIAQQVNLIE
410 420 430 440 450
NKEKVKMSKR LGIFQTMRDL LSYLGKNGKD VGRYFFLMRS SDAPLDFDLD
460 470 480 490 500
LAKDESDKNP VFYIQYAHAR ICSIFRELQI SIADWSIPKV VSGDCFQSEE
510 520 530 540 550
RLRLLFWVAR FQEEVYDTAT NLEPHRLTNY LQSLSKAFTK FYSHKDNRIK
560 570 580 590
EKQGEEREQL LFLILFTKRA IASGLELLGI SSPEKMSKED ESNT
Length:594
Mass (Da):68,753
Last modified:April 8, 2008 - v1
Checksum:iD11E0BDE79BB4F6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000777 Genomic DNA. Translation: ABZ94535.1.
RefSeqiWP_012389061.1. NC_010842.1.

Genome annotation databases

EnsemblBacteriaiABZ94535; ABZ94535; LBF_2035.
KEGGilbf:LBF_2035.

Similar proteinsi

Entry informationi

Entry nameiSYR_LEPBA
AccessioniPrimary (citable) accession number: B0SB29
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 8, 2008
Last modified: August 30, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families