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B0S8M3 (B0S8M3_LEPBA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2-dehydro-3-deoxyphosphooctonate aldolase HAMAP MF_00056
EC=2.5.1.55 HAMAP MF_00056
Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase HAMAP MF_00056
KDO-8-phosphate synthase HAMAP MF_00056
Phospho-2-dehydro-3-deoxyoctonate aldolase HAMAP MF_00056
Gene names
Name:kdsA HAMAP MF_00056 EMBL ABZ94104.1
Ordered Locus Names:LBF_1596
OrganismLeptospira biflexa serovar Patoc (strain Patoc 1 / Ames) [Complete proteome] [HAMAP]
Taxonomic identifier355278 [NCBI]
Taxonomic lineageBacteria › Spirochaetes › Spirochaetales › Leptospiraceae › Leptospira

Protein attributes

Sequence length281 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. HAMAP MF_00056 SAAS SAAS006269

Pathway

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP MF_00056 SAAS SAAS006269

Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. HAMAP MF_00056 SAAS SAAS006269

Subcellular location

Cytoplasm By similarity HAMAP MF_00056 SAAS SAAS006269.

Sequence similarities

Belongs to the KdsA family. HAMAP MF_00056

Sequences

Sequence LengthMass (Da)Tools
B0S8M3 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 6BBDD650EE975874

FASTA28131,385
        10         20         30         40         50         60 
MYDLIEEREF FGKKIGGRQP FFLISGPCVM ENKDLLDRVC GEMKAICDDL GIVYIFKSSF 

        70         80         90        100        110        120 
DKANRSSINS YRGPGLEEGR KLLDFIKNKY NVPVLTDIHE TIQVDPLKDT VDIFQIPAFL 

       130        140        150        160        170        180 
SRQTDLIAKA AETGKWVNVK KGQFMAPDDT RHIKTKIQES GSEKYMVTER GASFGYGNLV 

       190        200        210        220        230        240 
FDLRGIPMMH KHGIPIVFDG THSAQLPGAA GNITGGLREF IPHMMRGAVS VGVEGLFMEV 

       250        260        270        280 
HPDPEKALSD ATTQFPLAKA KSLLTQLLEL DRLVKTKFLE D

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References

[1]"Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis."
Picardeau M., Bulach D.M., Bouchier C., Zuerner R.L., Zidane N., Wilson P.J., Creno S., Kuczek E.S., Bommezzadri S., Davis J.C., McGrath A., Johnson M.J., Boursaux-Eude C., Seemann T., Rouy Z., Coppel R.L., Rood J.I., Lajus A. expand/collapse author list , Davies J.K., Medigue C., Adler B.
PLoS ONE 3:E1607-E1607(2008) [PubMed: 18270594] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000777 Genomic DNA. Translation: ABZ94104.1.
RefSeqYP_001962682.1. NC_010842.1.

3D structure databases

ProteinModelPortalB0S8M3.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0S8M3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6388193.
GenomeReviewsGene locus LBF_1596 in contig CP000777_GR.
KEGGlbf:LBF_1596.
PATRIC22342275. VBILepBif95142_1694.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG575990.
OMAHENEQCA.
ProtClustDBPRK05198.

Family and domain databases

HAMAPMF_00056. KDO8P_synth.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006269. KDO8P_synthase.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01627.
PANTHERPTHR21057:SF2. KDO8P_synthase. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR01362. KDO8P_synth. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB0S8M3_LEPBA
AccessionPrimary (citable) accession number: B0S8M3
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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