B0S6T1 (B0S6T1_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GLI-Kruppel family member GLI2a Ensembl ENSDARP00000010693 EMBL CAQ14572.1

Gene names

Name:	gli2a ZFIN ZDB-GENE-990706-8 Ensembl ENSDARP00000010693 EMBL AAI63542.1
ORF Names:	DKEY-25L23.1-001 EMBL CAQ14572.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL CAQ14572.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	1439 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	adenohypophysis morphogenesis Inferred from mutant phenotype. Source: ZFIN blood circulation Inferred from mutant phenotype. Source: ZFIN dorsal/ventral pattern formation Inferred from mutant phenotype. Source: ZFIN embryonic digestive tract morphogenesis Inferred from mutant phenotype. Source: ZFIN endocrine pancreas development Inferred from mutant phenotype. Source: ZFIN floor plate formation Inferred from mutant phenotype. Source: ZFIN glomerulus development Inferred from mutant phenotype. Source: ZFIN motor axon guidance Inferred from mutant phenotype. Source: ZFIN muscle cell fate specification Inferred from mutant phenotype. Source: ZFIN muscle organ development Inferred from mutant phenotype. Source: ZFIN optic nerve formation Inferred from mutant phenotype. Source: ZFIN post-embryonic foregut morphogenesis Inferred from mutant phenotype. Source: ZFIN regulation of neurogenesis Inferred from mutant phenotype. Source: ZFIN retinal ganglion cell axon guidance Inferred from mutant phenotype. Source: ZFIN somatic motor neuron differentiation Inferred from mutant phenotype. Source: ZFIN somitogenesis Inferred from mutant phenotype. Source: ZFIN striated muscle cell development Inferred from mutant phenotype. Source: ZFIN
Cellular component	nonmotile primary cilium Inferred from direct assay. Source: ZFIN nucleus Inferred from direct assay. Source: ZFIN
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0S6T1 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 9A103E2E17BE202B	FASTA	1,439	156,735
	10 20 30 40 50 60 METTSPTSTE KKELKPSVLD GSSFTDLPKK PSPTTASRAP HLFSTFHTPI PIDMRHHEGR 70 80 90 100 110 120 YHYEPHPLHP MHGPHGLAGS PVISDISLIR LSPHAAATGE SPFNPPHPYV NPHMEHYLRS 130 140 150 160 170 180 VHSSPTLSMI SAARGLSPAE LTHEHLKERS LFGLPPPPPG ANPSEYYHLI ASHRSPYGDL 190 200 210 220 230 240 LMQTGAAAAH LPDYMSPVDM SRFPSPRLTP RVSRKRALSI SPVSDASIDL QTMIRTSPNS 250 260 270 280 290 300 LVAYINNSRS SSAASSSYGH LSVGAISPSF TFPHPITPVA YHQLLSQQRG LNAFGHTPPL 310 320 330 340 350 360 LQPSPALSSR QQTLVAAAAL NNTTSSSTSS STADTSTESS QNAGGDPAVS STVNPMIFKR 370 380 390 400 410 420 SKVKTEAEGP HPISPGSQDH LELREELDKD ECKQEPEAVY ETNCHWEGCA KEYDTQDQLV 430 440 450 460 470 480 HHISNDHIHG EKKEFVCRWV ECSREQKPFK AQYMLVVHMR RHTGEKPHKC TFEGCSKAYS 490 500 510 520 530 540 RLENLKTHLR SHTGEKPYVC EHEGCNKAFS NASDRAKHQN RTHSNEKPYV CKIPGCTKRY 550 560 570 580 590 600 TDPSSLRKHV KTVHGPEAHV TKKQRGDAPP KPHPPKGNGE NEAHTKHVRG RTDGSGEANS 610 620 630 640 650 660 TTRGVEDCQH VKTIKTENTV MYQSSPGGQS SCSSEPSPLG SATNNDSGVE MAMHSGGSLG 670 680 690 700 710 720 DLSALDDTPV VDSTGSPGTS AGVGLQLRKN RAGLLQLEHI KKEKLKTVRD SCSWANAPPQ 730 740 750 760 770 780 VRNTKLPPIP SIDSLLDAPN IGTQMSVPPT QHLGDLSSYE MTMLNQLHER RDSSTSTMSS 790 800 810 820 830 840 AYISRRSSGI SPCYSSRRSS EASQFGVRNN NVSSADSYDP ISTDLSRRSS EASQCGGTGG 850 860 870 880 890 900 LPSLLNLTPA QHYSLKAKYA AATGGAPPTP LPNMDRMSLK TRMAMYNDSQ DSSAHLHHAQ 910 920 930 940 950 960 GVVNSRRCSD TGYGAPGIMP HEVPANLPRR ASDPVRRTTL DPLSLPRVQR FNSISNMNLS 970 980 990 1000 1010 1020 RLPAYDRRAF NMQNNTWSDG SLHRHPFSQR PPSISENILM ENMATDGGDQ QGDDLVLPDD 1030 1040 1050 1060 1070 1080 MVQYLRSQNG NSNHDSGISV NGGHALEFHG NMTSQQQQFY GQRRMGMASI NGSHVEPVPE 1090 1100 1110 1120 1130 1140 QIADPQGMNK NNMPVQWNEV SSGSADAVSR VPKQQQQQLR GNLTVVQQKQ NFGSYQGFGS 1150 1160 1170 1180 1190 1200 NQQIVPMSQN LASLQQAYPQ RNIQRMNTVQ QYRQSISNPC QNIGEQVNRQ DLSYNSNQRL 1210 1220 1230 1240 1250 1260 ICNSMGPPNG RVVQNQELQN YRSNLMHMNN INQQNYVPLT QTAIQNAGRG LIQPRPPSEP 1270 1280 1290 1300 1310 1320 KPLNRQHSGS GMVQPNGCSL SNVNSSEASP KRPGEVGQHS NGNGTMYYSG EIHMLDNGID 1330 1340 1350 1360 1370 1380 YGSPMSPCTN QAPVASVSTM ASPGVNQVTS TVDSTQSLDH TQIDFDAMLD DGDHSSLMSG 1390 1400 1410 1420 1430 TLSPGLLQSI SQNSSRLTTP RNSVTLASVP AGIGNMAIGD MSSMLTALAE ESKFLNMMA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pooled EMBL AAI63542.1.
[2]	Pelan S. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Murnane C. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000010693.
[5]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000010693.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC163542 mRNA. Translation: AAI63542.1. BX548071, CU013535 Genomic DNA. Translation: CAQ14572.1. CU013535, BX548071 Genomic DNA. Translation: CAQ15525.1.
IPI	IPI00510973.
UniGene	Dr.8091.
3D structure databases
ProteinModelPortal	B0S6T1.
SMR	B0S6T1. Positions 401-555.
ModBase	Search...
Protein-protein interaction databases
STRING	B0S6T1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000024555; ENSDARP00000010693; ENSDARG00000025641.
Organism-specific databases
ZFIN	ZDB-GENE-990706-8. gli2a.
Phylogenomic databases
HOGENOM	HBG447235.
HOVERGEN	HBG005844.
OMA	MASPGVN.
OrthoDB	EOG4V16ZZ.
PhylomeDB	B0S6T1.
Gene expression databases
Bgee	B0S6T1.
Family and domain databases
InterPro	IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. IPR013087. Znf_C2H2/integrase_DNA-bd. [Graphical view]
Gene3D	G3DSA:3.30.160.60. Znf_C2H2/integrase_DNA-bd. 4 hits.
Pfam	PF00096. zf-C2H2. 4 hits. [Graphical view]
SMART	SM00355. ZnF_C2H2. 5 hits. [Graphical view]
PROSITE	PS00028. ZINC_FINGER_C2H2_1. 4 hits. PS50157. ZINC_FINGER_C2H2_2. 4 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B0S6T1_DANRE

Accession

Primary (citable) accession number: B0S6T1

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)