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B0S1H0 (PGK_FINM2) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:FMG_0792
OrganismFinegoldia magna (strain ATCC 29328) (Peptostreptococcus magnus) [Complete proteome] [HAMAP]
Taxonomic identifier334413 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiales Family XI. Incertae SedisFinegoldia

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 395395Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000096343

Regions

Nucleotide binding351 – 3544ATP By similarity
Region21 – 233Substrate binding By similarity
Region59 – 624Substrate binding By similarity

Sites

Binding site361Substrate By similarity
Binding site1201Substrate By similarity
Binding site1531Substrate By similarity
Binding site2031ATP By similarity
Binding site2941ATP; via carbonyl oxygen By similarity
Binding site3251ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
B0S1H0 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 6FAA5915BF1AC831

FASTA39543,378
        10         20         30         40         50         60 
MNKKTLKDLN VENKRVLVRV DFNVPIKEGI ITDTNRIEAS LTTIKYLIDN NAKVILMSHL 

        70         80         90        100        110        120 
GRPKGEPKPE FSLKPVAQKL SEMIGQDVKF IDSDKVVDDS VIEESKKLQP KEIMLIQNTR 

       130        140        150        160        170        180 
FRKEEEKNDQ TFSKELSQLA DLYVNDAFGT SHRAHASNVG VSKFLPSAVG FLVQKEIEIM 

       190        200        210        220        230        240 
GKALENPERP FTAILGGAKV SDKIGVIENL LDKVDTILIG GAMAFTFIKS QGKNVGKSLI 

       250        260        270        280        290        300 
EEDKLDLAKS LLEKAQEKGV KIFLPVDFVV AKEMTEESDS KVINIDDFTD DIAGFDIGTK 

       310        320        330        340        350        360 
TIKIFDEEIQ KSKTIVWNGP MGVFEIEQFS KGTFEIANSL VKSKAITIVG GGDSASAIAK 

       370        380        390 
SGNKDKVTHV STGGGASLEF LEGKVLPGID CIDER 

« Hide

References

[1]"Complete genome sequence of Finegoldia magna, an anaerobic opportunistic pathogen."
Goto T., Yamashita A., Hirakawa H., Matsutani M., Todo K., Ohshima K., Toh H., Miyamoto K., Kuhara S., Hattori M., Shimizu T., Akimoto S.
DNA Res. 15:39-47(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29328.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008971 Genomic DNA. Translation: BAG08210.1.
RefSeqYP_001692100.1. NC_010376.1.

3D structure databases

ProteinModelPortalB0S1H0.
SMRB0S1H0. Positions 2-395.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING334413.FMG_0792.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAG08210; BAG08210; FMG_0792.
GeneID6018613.
KEGGfma:FMG_0792.
PATRIC21887261. VBIFinMag33027_0997.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227108.
KOK00927.
OMAFGLADKM.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycFMAG334413:GJ6M-843-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_FINM2
AccessionPrimary (citable) accession number: B0S1H0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: February 19, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways