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Protein

Thymidine kinase

Gene

tdk

Organism
Finegoldia magna (strain ATCC 29328) (Peptostreptococcus magnus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei88Proton acceptorUniRule annotation1
Metal bindingi147ZincUniRule annotation1
Metal bindingi150ZincUniRule annotation1
Metal bindingi179ZincUniRule annotation1
Metal bindingi182ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 20ATPUniRule annotation8
Nucleotide bindingi87 – 90ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:FMG_0715Imported
OrganismiFinegoldia magna (strain ATCC 29328) (Peptostreptococcus magnus)Imported
Taxonomic identifieri334413 [NCBI]
Taxonomic lineageiBacteriaFirmicutesTissierelliaTissierellalesPeptoniphilaceaeFinegoldia
Proteomesi
  • UP000001319 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi334413.FMG_0715

Structurei

3D structure databases

ProteinModelPortaliB0S193
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107104 Bacteria
COG1435 LUCA
HOGENOMiHOG000076390
KOiK00857
OMAiCAGLDQD
OrthoDBiPOG091H0659

Family and domain databases

HAMAPiMF_00124 Thymidine_kinase, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
IPR020633 Thymidine_kinase_CS
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00603 TK_CELLULAR_TYPE, 1 hit

Sequencei

Sequence statusi: Complete.

B0S193-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHQYKGKLIV HTGSMFSGKT SSLWKEVNRF KIAKYNVVVF KPRMDSRYSK
60 70 80 90 100
EKVVTHDKNE IEAINVDNID DIVEYTKTHD VNVIAIDEIQ FINSKADHFV
110 120 130 140 150
KQINYLLEKG FTIIAAGLDM DYKAKPFQLV KELLPICDYV EKHHAVCAVC
160 170 180 190 200
GNDAWVSYRI SDDKNRIQLG ANEAYMPLCR KHYIEKMNEK RFTELQTTYL
210
DKNRAKKNTI
Length:210
Mass (Da):24,471
Last modified:April 8, 2008 - v1
Checksum:i8354BABA4AEF48E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008971 Genomic DNA Translation: BAG08133.1
RefSeqiWP_012290582.1, NC_010376.1

Genome annotation databases

EnsemblBacteriaiBAG08133; BAG08133; FMG_0715
GeneIDi34165843
KEGGifma:FMG_0715

Similar proteinsi

Entry informationi

Entry nameiB0S193_FINM2
AccessioniPrimary (citable) accession number: B0S193
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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