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B0S0R2

- PUR5_FINM2

UniProt

B0S0R2 - PUR5_FINM2

Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Finegoldia magna (strain ATCC 29328) (Peptostreptococcus magnus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Purine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciFMAG334413:GJ6M-328-MONOMER.
    UniPathwayiUPA00074; UER00129.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
    Alternative name(s):
    AIR synthaseUniRule annotation
    AIRSUniRule annotation
    Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
    Gene namesi
    Name:purMUniRule annotation
    Ordered Locus Names:FMG_0311
    OrganismiFinegoldia magna (strain ATCC 29328) (Peptostreptococcus magnus)
    Taxonomic identifieri334413 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiales Family XI. Incertae SedisFinegoldia
    ProteomesiUP000001319: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 341341Phosphoribosylformylglycinamidine cyclo-ligasePRO_1000193025Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi334413.FMG_0311.

    Structurei

    3D structure databases

    ProteinModelPortaliB0S0R2.
    SMRiB0S0R2. Positions 17-330.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AIR synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0150.
    HOGENOMiHOG000229090.
    KOiK01933.
    OMAiIKLAMEL.
    OrthoDBiEOG61CM1V.

    Family and domain databases

    Gene3Di3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPiMF_00741_B. AIRS_B.
    InterProiIPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view]
    PfamiPF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsiTIGR00878. purM. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B0S0R2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGLTYKDSGV DKEKGYEEVQ IIKEIVKKTH GKEVLTGIGG FAGLFKPELT    50
    DMKEPVLVSG TDGVGTKIKL AMELDKHDTV GIDLVAMCVN DVLCQGAKPL 100
    FFLDYIATGS LKPAKMADLV RGVAEGCSQS ECALIGGETA EMPGLYKEND 150
    YDLAGFAVGI VDRDKIIDGS GIKEGDVAIS LSSSGVHSNG FSLVRAALDM 200
    ANVKLSDKFE DTTVGERLLV PTRIYEKEIS ALLKEVEIKG IAHITGGGLY 250
    ENVPRMLPEN IGIEFDIKES EIDSVFKAIQ KWGNVETKEM FSTFNMGIGM 300
    VVVVDAKDVD KSLEILQKID PKAKQCGVCK KTETSVKINL K 341
    Length:341
    Mass (Da):36,848
    Last modified:April 8, 2008 - v1
    Checksum:i49F1AD2557FE319D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008971 Genomic DNA. Translation: BAG07729.1.
    RefSeqiYP_001691619.1. NC_010376.1.

    Genome annotation databases

    EnsemblBacteriaiBAG07729; BAG07729; FMG_0311.
    GeneIDi6019065.
    KEGGifma:FMG_0311.
    PATRICi21886231. VBIFinMag33027_0516.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008971 Genomic DNA. Translation: BAG07729.1 .
    RefSeqi YP_001691619.1. NC_010376.1.

    3D structure databases

    ProteinModelPortali B0S0R2.
    SMRi B0S0R2. Positions 17-330.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 334413.FMG_0311.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAG07729 ; BAG07729 ; FMG_0311 .
    GeneIDi 6019065.
    KEGGi fma:FMG_0311.
    PATRICi 21886231. VBIFinMag33027_0516.

    Phylogenomic databases

    eggNOGi COG0150.
    HOGENOMi HOG000229090.
    KOi K01933.
    OMAi IKLAMEL.
    OrthoDBi EOG61CM1V.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00129 .
    BioCyci FMAG334413:GJ6M-328-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPi MF_00741_B. AIRS_B.
    InterProi IPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view ]
    Pfami PF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsi TIGR00878. purM. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Finegoldia magna, an anaerobic opportunistic pathogen."
      Goto T., Yamashita A., Hirakawa H., Matsutani M., Todo K., Ohshima K., Toh H., Miyamoto K., Kuhara S., Hattori M., Shimizu T., Akimoto S.
      DNA Res. 15:39-47(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29328.

    Entry informationi

    Entry nameiPUR5_FINM2
    AccessioniPrimary (citable) accession number: B0S0R2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3