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Protein

Catalase-peroxidase

Gene

katG

Organism
Xanthomonas campestris pv. campestris (strain B100)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.UniRule annotation

Catalytic activityi

Donor + H2O2 = oxidized donor + 2 H2O.UniRule annotation
2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

heme bUniRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei89Transition state stabilizerUniRule annotation1
Active sitei93Proton acceptorUniRule annotation1
Metal bindingi279Iron (heme axial ligand)UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxide

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase-peroxidaseUniRule annotation (EC:1.11.1.21UniRule annotation)
Short name:
CPUniRule annotation
Alternative name(s):
Peroxidase/catalaseUniRule annotation
Gene namesi
Name:katGUniRule annotation
Ordered Locus Names:xcc-b100_3134
OrganismiXanthomonas campestris pv. campestris (strain B100)
Taxonomic identifieri509169 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000001188 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003549571 – 748Catalase-peroxidaseAdd BLAST748

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki92 ↔ 238Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-264)UniRule annotation
Cross-linki238 ↔ 264Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-92)UniRule annotation

Post-translational modificationi

The covalent Trp-Tyr-Met adduct is important for the catalase, but not the peroxidase activity of the enzyme.UniRule annotation

Interactioni

Subunit structurei

Homodimer or homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB0RXD3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxidase family. Peroxidase/catalase subfamily.UniRule annotation

Phylogenomic databases

KOiK03782.
OMAiIAEVYAC.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0RXD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTEAKCPFN HSVVGAGTTN RDWWPKQLRV DLLNQHSARS NPLAASFNYA
60 70 80 90 100
EAFKRLDLQT LKQELRALMT DSQDWWPADF GHYGPLFVRM AWHSAGTYRT
110 120 130 140 150
GDGRGGGGRG QQRFAPLNSW PDNVSLDKAR RLLWPIKQKY GQAISWADLM
160 170 180 190 200
ILTGNVALES MGFKTFGFAG GREDTWEPDQ DLYWGRETKW LGGDDRYAHG
210 220 230 240 250
SPGVDQAHGV LVKDDDSEVQ HTRDLENPLA AVQMGLIYVN PEGPDGNPDP
260 270 280 290 300
LLAAKDIRDT FGRMAMNDEE TVALIAGGHT FGKTHGAADA AHVAAEPEAS
310 320 330 340 350
DLESQGLGWH NSFGSGKGGD TITSGLEVTW TTTPAQWSND FFDHLFGFEW
360 370 380 390 400
ELSKSPAGAH QWVAKNAQAI IPDAHDASKK RLPTMLTTDL ALRIDPAYEA
410 420 430 440 450
ISRRFHANPD QFADAFARAW FKLTHRDMGP RARYLGADVP AEELLWQDPI
460 470 480 490 500
PALNHALIDA QDAAALKQTV LSSGLSVAQL VATAWASASS FRGSDKRGGA
510 520 530 540 550
NGARIRLAPQ KDWASNEPAQ LAQVLATLER IQADFNARQS GGKQISLADL
560 570 580 590 600
IVLGGNAAVE QAAHAAGHAV TVPFAPGRMD ASQAQTDVES FAVLEPVADG
610 620 630 640 650
FRNYAKARYA VSAEALLIDK AQLLTLTAPE MTVLVGGLRV LGANTGQSHN
660 670 680 690 700
GVFTTRPGVL SNDFFANLLD MRTEWKATSE TKETYEGRDR ATGEHKWTGT
710 720 730 740
RVDLVFGSNS ILRAVAEVYA SADAQEKFVQ DFVAAWTKVM QLDRFDLA
Length:748
Mass (Da):81,593
Last modified:May 20, 2008 - v1
Checksum:i823A7AB8BE3D9C57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM920689 Genomic DNA. Translation: CAP52499.1.

Genome annotation databases

EnsemblBacteriaiCAP52499; CAP52499; xcc-b100_3134.
KEGGixca:xcc-b100_3134.
PATRICi24086152. VBIXanCam108527_3154.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM920689 Genomic DNA. Translation: CAP52499.1.

3D structure databases

ProteinModelPortaliB0RXD3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAP52499; CAP52499; xcc-b100_3134.
KEGGixca:xcc-b100_3134.
PATRICi24086152. VBIXanCam108527_3154.

Phylogenomic databases

KOiK03782.
OMAiIAEVYAC.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiKATG_XANCB
AccessioniPrimary (citable) accession number: B0RXD3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: May 20, 2008
Last modified: November 2, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.