Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B0RWQ7 (B0RWQ7_XANCB) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Methionyl-tRNA formyltransferase HAMAP-Rule MF_00182

EC=2.1.2.9 HAMAP-Rule MF_00182
Gene names
Name:fmt HAMAP-Rule MF_00182
Ordered Locus Names:xcc-b100_3929 EMBL CAP53296.1
OrganismXanthomonas campestris pv. campestris (strain B100) [Complete proteome] [HAMAP]
Taxonomic identifier509169 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP By similarity. HAMAP-Rule MF_00182 SAAS SAAS005794

Catalytic activity

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet). SAAS SAAS005794 HAMAP-Rule MF_00182

Sequence similarities

Belongs to the Fmt family. HAMAP-Rule MF_00182

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region153 – 1564Tetrahydrofolate (THF) binding By similarity HAMAP-Rule MF_00182

Sequences

Sequence LengthMass (Da)Tools
B0RWQ7 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: A713BEAD803F6448

FASTA35237,274
        10         20         30         40         50         60 
MPLSAPVAKP ARATVHPIYQ FHAATVPAST SAVANPQSRL PNPSPMRIVF AGTPDFAVAS 

        70         80         90        100        110        120 
LRAAAQLHEV VAVYTQPDRP AGRGRGLTPS PVKLDAIARG IPVFQPQTLR SPEALATLRA 

       130        140        150        160        170        180 
LQPDLMVVVA YGLILPKAVL AASTHGCWNV HASLLPRWRG AAPIQRAIEA GDTETGVCLM 

       190        200        210        220        230        240 
QMEAGLDTGP VLLSQRIEIG EQETGGQLHD RLAALGAQVL SDGLGLLRAG IRPVAQPQPA 

       250        260        270        280        290        300 
EGVTYAHKLD KAQARLDWAQ PAEELARRVR AFNPWPVAEA ILAGERVRLH GAVALDLAHR 

       310        320        330        340        350 
QAPGTLLAAS KQGIDIACGQ GALRVRVLQR EGGKAITAAD YLNARRDLPA LR 

« Hide

References

[1]"The genome of Xanthomonas campestris pv. campestris B100 and its use for the reconstruction of metabolic pathways involved in xanthan biosynthesis."
Vorhoelter F.-J., Schneiker S., Goesmann A., Krause L., Bekel T., Kaiser O., Linke B., Patschkowski T., Rueckert C., Schmid J., Sidhu V.K., Sieber V., Tauch A., Watt S.A., Weisshaar B., Becker A., Niehaus K., Puehler A.
J. Biotechnol. 134:33-45(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B100 EMBL CAP53296.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM920689 Genomic DNA. Translation: CAP53296.1.
RefSeqYP_001905334.1. NC_010688.1.

3D structure databases

ProteinModelPortalB0RWQ7.
SMRB0RWQ7. Positions 44-347.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING509169.xccb100_3929.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAP53296; CAP53296; xcc-b100_3929.
GeneID6323738.
KEGGxca:xccb100_3929.
PATRIC24087822. VBIXanCam108527_3971.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0223.
KOK00604.
OMAFDKITPK.
OrthoDBEOG6B09WV.
ProtClustDBPRK00005.

Enzyme and pathway databases

BioCycXCAM509169:GHW4-4017-MONOMER.

Family and domain databases

Gene3D3.10.25.10. 1 hit.
3.40.50.170. 1 hit.
HAMAPMF_00182. Formyl_trans.
InterProIPR005794. Fmt.
IPR005793. Formyl_trans_C.
IPR002376. Formyl_transf_N.
IPR011034. Formyl_transferase_C-like.
IPR001555. GART_AS.
IPR015518. Met_tRNA_Form_TA-like.
[Graphical view]
PANTHERPTHR11138. PTHR11138. 1 hit.
PfamPF02911. Formyl_trans_C. 1 hit.
PF00551. Formyl_trans_N. 1 hit.
[Graphical view]
SUPFAMSSF50486. SSF50486. 1 hit.
SSF53328. SSF53328. 1 hit.
TIGRFAMsTIGR00460. fmt. 1 hit.
PROSITEPS00373. GART. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0RWQ7_XANCB
AccessionPrimary (citable) accession number: B0RWQ7
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: April 16, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)