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B0RVK6

- XANB_XANCB

UniProt

B0RVK6 - XANB_XANCB

Protein

Xanthan biosynthesis protein XanB

Gene

xanB

Organism
Xanthomonas campestris pv. campestris (strain B100)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    Involved in xanthan production.

    Catalytic activityi

    D-mannose 6-phosphate = D-fructose 6-phosphate.
    GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose.

    Pathwayi

    GO - Molecular functioni

    1. GTP binding Source: UniProtKB-KW
    2. mannose-1-phosphate guanylyltransferase activity Source: UniProtKB-EC
    3. mannose-6-phosphate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. GDP-mannose biosynthetic process Source: UniProtKB-UniPathway
    2. lipopolysaccharide biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Isomerase, Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    Exopolysaccharide synthesis, Lipopolysaccharide biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRETL1328306-WGS:GSTH-3299-MONOMER.
    XCAM509169:GHW4-3816-MONOMER.
    UniPathwayiUPA00126; UER00423.
    UPA00126; UER00930.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xanthan biosynthesis protein XanB
    Including the following 2 domains:
    Mannose-6-phosphate isomerase (EC:5.3.1.8)
    Alternative name(s):
    Phosphohexomutase
    Phosphomannose isomerase
    Short name:
    PMI
    Mannose-1-phosphate guanylyl transferase (EC:2.7.7.13)
    Alternative name(s):
    GDP-mannose pyrophosphorylase
    Short name:
    GMP
    Short name:
    GMPP
    Gene namesi
    Name:xanB
    Ordered Locus Names:xcc-b100_3730
    OrganismiXanthomonas campestris pv. campestris (strain B100)
    Taxonomic identifieri509169 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
    ProteomesiUP000001188: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 467467Xanthan biosynthesis protein XanBPRO_0000333187Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi509169.xccb100_3730.

    Structurei

    3D structure databases

    ProteinModelPortaliB0RVK6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0662.
    KOiK16011.
    OMAiIYAACEQ.
    OrthoDBiEOG6X3W6T.

    Family and domain databases

    Gene3Di2.60.120.10. 1 hit.
    3.90.550.10. 1 hit.
    InterProiIPR006375. Man1P_GuaTrfase/Man6P_Isoase.
    IPR001538. Man6P_isomerase-2_C.
    IPR005835. NTP_transferase.
    IPR029044. Nucleotide-diphossugar_trans.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view]
    PfamiPF01050. MannoseP_isomer. 1 hit.
    PF00483. NTP_transferase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51182. SSF51182. 1 hit.
    SSF53448. SSF53448. 1 hit.
    TIGRFAMsiTIGR01479. GMP_PMI. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B0RVK6-1 [UniParc]FASTAAdd to Basket

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    MSDVLPIILS GGSGTRLWPL SRETYPKQFL PLVGEHSMLQ ATWLRSAPVA    50
    AHAPIVVANE EHRFMAAEQL QQLGVKPSAI LLEPKGRNTA PAIAVAALEA 100
    TRNGGDPLLL VLPSDHVIRD EAAFQAAVTV AAAAAEQGKL VTFGIKPTAP 150
    ETGYGYIKAG AGTGATAVER FVEKPDLATA QGYLASGEYY WNSGMFLFRA 200
    SRYLEELRKF QPAIADACQK AWEGGKRDAD FTRLDKDAFA SSPSDSIDYA 250
    VMEKTADAVV VPLDAGWNDV GSWSSLLDVS EQDGQGNAHH GDVIQLDCKN 300
    TYAYGSRLIA MVGLENVVVV ETDDAVLVGH RDRIQEVKEV VSQIKSAGRS 350
    EATWHRKVYR PWGAYDSIDM GQRFQVKRIT VKPGATLSLQ MHHHRAEHWI 400
    VVSGTAEVTR GDEVLLLTEN QSTYIPLGVT HRLKNPGKLP LELIEVQSGS 450
    YLGEDDIVRF EDTYGRT 467
    Length:467
    Mass (Da):50,934
    Last modified:April 8, 2008 - v1
    Checksum:i596DEEFFA93FC78A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF204145 Genomic DNA. Translation: AAK53463.1.
    AM920689 Genomic DNA. Translation: CAP53097.1.
    PIRiB43304.
    RefSeqiYP_001905135.1. NC_010688.1.

    Genome annotation databases

    EnsemblBacteriaiCAP53097; CAP53097; xcc-b100_3730.
    GeneIDi6325210.
    KEGGixca:xccb100_3730.
    PATRICi24087412. VBIXanCam108527_3767.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF204145 Genomic DNA. Translation: AAK53463.1 .
    AM920689 Genomic DNA. Translation: CAP53097.1 .
    PIRi B43304.
    RefSeqi YP_001905135.1. NC_010688.1.

    3D structure databases

    ProteinModelPortali B0RVK6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 509169.xccb100_3730.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAP53097 ; CAP53097 ; xcc-b100_3730 .
    GeneIDi 6325210.
    KEGGi xca:xccb100_3730.
    PATRICi 24087412. VBIXanCam108527_3767.

    Phylogenomic databases

    eggNOGi COG0662.
    KOi K16011.
    OMAi IYAACEQ.
    OrthoDBi EOG6X3W6T.

    Enzyme and pathway databases

    UniPathwayi UPA00126 ; UER00423 .
    UPA00126 ; UER00930 .
    BioCyci RETL1328306-WGS:GSTH-3299-MONOMER.
    XCAM509169:GHW4-3816-MONOMER.

    Family and domain databases

    Gene3Di 2.60.120.10. 1 hit.
    3.90.550.10. 1 hit.
    InterProi IPR006375. Man1P_GuaTrfase/Man6P_Isoase.
    IPR001538. Man6P_isomerase-2_C.
    IPR005835. NTP_transferase.
    IPR029044. Nucleotide-diphossugar_trans.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view ]
    Pfami PF01050. MannoseP_isomer. 1 hit.
    PF00483. NTP_transferase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51182. SSF51182. 1 hit.
    SSF53448. SSF53448. 1 hit.
    TIGRFAMsi TIGR01479. GMP_PMI. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genetics of xanthan production in Xanthomonas campestris: the xanA and xanB genes are involved in UDP-glucose and GDP-mannose biosynthesis."
      Koeplin R., Arnold W., Hoette B., Simon R., Wang G., Puehler A.
      J. Bacteriol. 174:191-199(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Lipopolysaccharide biosynthesis in Xanthomonas campestris pv. campestris: a cluster of 15 genes is involved in the biosynthesis of the LPS O-antigen and the LPS core."
      Vorhoelter F.-J., Niehaus K., Puehler A.
      Mol. Genet. Genomics 266:79-95(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION TO 164.
    3. "The genome of Xanthomonas campestris pv. campestris B100 and its use for the reconstruction of metabolic pathways involved in xanthan biosynthesis."
      Vorhoelter F.-J., Schneiker S., Goesmann A., Krause L., Bekel T., Kaiser O., Linke B., Patschkowski T., Rueckert C., Schmid J., Sidhu V.K., Sieber V., Tauch A., Watt S.A., Weisshaar B., Becker A., Niehaus K., Puehler A.
      J. Biotechnol. 134:33-45(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: B100.

    Entry informationi

    Entry nameiXANB_XANCB
    AccessioniPrimary (citable) accession number: B0RVK6
    Secondary accession number(s): P29956, Q93S98
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Multifunctional enzyme

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3