Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Xanthan biosynthesis protein XanB

Gene

xanB

Organism
Xanthomonas campestris pv. campestris (strain B100)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in xanthan production.

Catalytic activityi

D-mannose 6-phosphate = D-fructose 6-phosphate.
GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose.

Pathwayi: GDP-alpha-D-mannose biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route).
Proteins known to be involved in this subpathway in this organism are:
  1. Xanthan biosynthesis protein XanB (xanB)
This subpathway is part of the pathway GDP-alpha-D-mannose biosynthesis, which is itself part of Nucleotide-sugar biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route), the pathway GDP-alpha-D-mannose biosynthesis and in Nucleotide-sugar biosynthesis.

Pathwayi: GDP-alpha-D-mannose biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes alpha-D-mannose 1-phosphate from D-fructose 6-phosphate.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Xanthan biosynthesis protein XanB (xanB)
  2. Phosphohexose mutases (xanA)
This subpathway is part of the pathway GDP-alpha-D-mannose biosynthesis, which is itself part of Nucleotide-sugar biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes alpha-D-mannose 1-phosphate from D-fructose 6-phosphate, the pathway GDP-alpha-D-mannose biosynthesis and in Nucleotide-sugar biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase, Multifunctional enzyme, Nucleotidyltransferase, Transferase
Biological processExopolysaccharide synthesis, Lipopolysaccharide biosynthesis
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00126; UER00423
UPA00126; UER00930

Names & Taxonomyi

Protein namesi
Recommended name:
Xanthan biosynthesis protein XanB
Including the following 2 domains:
Mannose-6-phosphate isomerase (EC:5.3.1.8)
Alternative name(s):
Phosphohexomutase
Phosphomannose isomerase
Short name:
PMI
Mannose-1-phosphate guanylyl transferase (EC:2.7.7.13)
Alternative name(s):
GDP-mannose pyrophosphorylase
Short name:
GMP
Short name:
GMPP
Gene namesi
Name:xanB
Ordered Locus Names:xcc-b100_3730
OrganismiXanthomonas campestris pv. campestris (strain B100)
Taxonomic identifieri509169 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000001188 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003331871 – 467Xanthan biosynthesis protein XanBAdd BLAST467

Proteomic databases

PRIDEiB0RVK6

Structurei

3D structure databases

ProteinModelPortaliB0RVK6
SMRiB0RVK6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK16011
OMAiIEDVYSW

Family and domain databases

Gene3Di2.60.120.10, 1 hit
3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR006375 Man1P_GuaTrfase/Man6P_Isoase
IPR001538 Man6P_isomerase-2_C
IPR005835 NTP_transferase_dom
IPR029044 Nucleotide-diphossugar_trans
IPR014710 RmlC-like_jellyroll
IPR011051 RmlC_Cupin_sf
PfamiView protein in Pfam
PF01050 MannoseP_isomer, 1 hit
PF00483 NTP_transferase, 1 hit
SUPFAMiSSF51182 SSF51182, 1 hit
SSF53448 SSF53448, 1 hit
TIGRFAMsiTIGR01479 GMP_PMI, 1 hit

Sequencei

Sequence statusi: Complete.

B0RVK6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDVLPIILS GGSGTRLWPL SRETYPKQFL PLVGEHSMLQ ATWLRSAPVA
60 70 80 90 100
AHAPIVVANE EHRFMAAEQL QQLGVKPSAI LLEPKGRNTA PAIAVAALEA
110 120 130 140 150
TRNGGDPLLL VLPSDHVIRD EAAFQAAVTV AAAAAEQGKL VTFGIKPTAP
160 170 180 190 200
ETGYGYIKAG AGTGATAVER FVEKPDLATA QGYLASGEYY WNSGMFLFRA
210 220 230 240 250
SRYLEELRKF QPAIADACQK AWEGGKRDAD FTRLDKDAFA SSPSDSIDYA
260 270 280 290 300
VMEKTADAVV VPLDAGWNDV GSWSSLLDVS EQDGQGNAHH GDVIQLDCKN
310 320 330 340 350
TYAYGSRLIA MVGLENVVVV ETDDAVLVGH RDRIQEVKEV VSQIKSAGRS
360 370 380 390 400
EATWHRKVYR PWGAYDSIDM GQRFQVKRIT VKPGATLSLQ MHHHRAEHWI
410 420 430 440 450
VVSGTAEVTR GDEVLLLTEN QSTYIPLGVT HRLKNPGKLP LELIEVQSGS
460
YLGEDDIVRF EDTYGRT
Length:467
Mass (Da):50,934
Last modified:April 8, 2008 - v1
Checksum:i596DEEFFA93FC78A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF204145 Genomic DNA Translation: AAK53463.1
AM920689 Genomic DNA Translation: CAP53097.1
PIRiB43304

Genome annotation databases

EnsemblBacteriaiCAP53097; CAP53097; xcc-b100_3730
KEGGixca:xcc-b100_3730

Similar proteinsi

Entry informationi

Entry nameiXANB_XANCB
AccessioniPrimary (citable) accession number: B0RVK6
Secondary accession number(s): P29956, Q93S98
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health