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B0RVK5 (XANA_XANCB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphohexose mutases

Including the following 2 domains:

  1. Phosphoglucomutase
    Short name=PGM
    EC=5.4.2.2
    Alternative name(s):
    Glucose phosphomutase
  2. Phosphomannomutase
    Short name=PMM
    EC=5.4.2.8
Gene names
Name:xanA
Ordered Locus Names:xcc-b100_3729
OrganismXanthomonas campestris pv. campestris (strain B100) [Complete proteome] [HAMAP]
Taxonomic identifier509169 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length448 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in xanthan production.

Catalytic activity

Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.

Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.

Cofactor

Binds 1 magnesium ion per subunit By similarity.

Pathway

Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.

Sequence similarities

Belongs to the phosphohexose mutase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 448448Phosphohexose mutases
PRO_0000333186

Sites

Active site971Phosphoserine intermediate By similarity
Metal binding971Magnesium; via phosphate group By similarity
Metal binding2371Magnesium By similarity
Metal binding2391Magnesium By similarity
Metal binding2411Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
B0RVK5 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 221961862CAEAB8F

FASTA44848,922
        10         20         30         40         50         60 
MTLPAFKAYD IRGRVPDELN EDLARRIGVA LAAQLDQGPV VLGHDVRLAS PALQEALSAG 

        70         80         90        100        110        120 
LRASGREVID IGLCGTEEVY FQTDHLKAAG GVMVTASHNP MDYNGMKLVR EQARPISSDT 

       130        140        150        160        170        180 
GLFAIRDTVA ADTAAAGEPT AAEHSRTDKT AYLEHLLSYV DRSTLKPLKL VVNAGNGGAG 

       190        200        210        220        230        240 
LIVDLLAPHL PFEFVRVFHE PDGNFPNGIP NPLLQENRDA TAKAVKEHGA DFGIAWDGDF 

       250        260        270        280        290        300 
DRCFFFDHTG RFIEGYYLVG LLAQAILAKQ PGGKVVHDPR LTWNTVEMVE DAGGIPVLCK 

       310        320        330        340        350        360 
SGHAFIKEKM RSENAVYGGE MSAHHYFREF AYADSGMIPW LLIAELVSQS GRSLADLVEA 

       370        380        390        400        410        420 
RMQKFPCSGE INFKVDDAKA AVARVMAHYG DQSPELDYTD GISADFGQWR FNLRSSNTEP 

       430        440 
LLRLNVETRG DAALLETRTQ EISNLLRG 

« Hide

References

« Hide 'large scale' references
[1]"Genetics of xanthan production in Xanthomonas campestris: the xanA and xanB genes are involved in UDP-glucose and GDP-mannose biosynthesis."
Koeplin R., Arnold W., Hoette B., Simon R., Wang G., Puehler A.
J. Bacteriol. 174:191-199(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The genome of Xanthomonas campestris pv. campestris B100 and its use for the reconstruction of metabolic pathways involved in xanthan biosynthesis."
Vorhoelter F.-J., Schneiker S., Goesmann A., Krause L., Bekel T., Kaiser O., Linke B., Patschkowski T., Rueckert C., Schmid J., Sidhu V.K., Sieber V., Tauch A., Watt S.A., Weisshaar B., Becker A., Niehaus K., Puehler A.
J. Biotechnol. 134:33-45(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B100.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF204145 Genomic DNA. Translation: AAA27610.1.
AM920689 Genomic DNA. Translation: CAP53096.1.
PIRA43304.
RefSeqYP_001905134.1. NC_010688.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING509169.xccb100_3729.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAP53096; CAP53096; xcc-b100_3729.
GeneID6325197.
KEGGxca:xccb100_3729.
PATRIC24087410. VBIXanCam108527_3766.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1109.
KOK15778.
OMAVVGCDIR.
OrthoDBEOG6W9X55.

Enzyme and pathway databases

BioCycXCAM509169:GHW4-3815-MONOMER.
UniPathwayUPA00126; UER00424.

Family and domain databases

Gene3D3.30.310.50. 1 hit.
3.40.120.10. 3 hits.
InterProIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
IPR005841. Alpha-D-phosphohexomutase_SF.
[Graphical view]
PfamPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
PRINTSPR00509. PGMPMM.
SUPFAMSSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEPS00710. PGM_PMM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXANA_XANCB
AccessionPrimary (citable) accession number: B0RVK5
Secondary accession number(s): P29955
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: May 14, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways