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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Xanthomonas campestris pv. campestris (strain B100)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi487MagnesiumUniRule annotation1
Metal bindingi493MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, RNA-binding, Transferase
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
Ordered Locus Names:xcc-b100_1653
OrganismiXanthomonas campestris pv. campestris (strain B100)
Taxonomic identifieri509169 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000001188 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003819261 – 704Polyribonucleotide nucleotidyltransferaseAdd BLAST704

Proteomic databases

PRIDEiB0RRB8

Interactioni

Subunit structurei

Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB0RRB8
SMRiB0RRB8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini554 – 613KHUniRule annotationAdd BLAST60
Domaini623 – 691S1 motifUniRule annotationAdd BLAST69

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Phylogenomic databases

KOiK00962

Family and domain databases

Gene3Di3.30.1370.10, 1 hit
3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR036456 PNPase_PH_RNA-bd_sf
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 2 hits
PF00575 S1, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF46915 SSF46915, 1 hit
SSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50084 KH_TYPE_1, 1 hit
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

B0RRB8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKITKTFQY GKHTVTLETG EVARQASGAV IVKMDDTVLL VTAVAAKTAR
60 70 80 90 100
EGQDFFPLTV DYQEKFYAGG RIPGGFFKRE GRATEKETLI SRLIDRPIRP
110 120 130 140 150
LFPEDYKNEV QIIATVMSMN PDIDGDIAAL IGASAALSLA GTPFNGPIGA
160 170 180 190 200
AKVGYKNGEY ILNPTITELK DSQLELVVAG TANAVLMVES EAALLSEEVM
210 220 230 240 250
LGAVTFGHRE MQKVINIINE LTVEAGTKPS TWVAPAKNTA LISALKEAVG
260 270 280 290 300
AQLAGAFQVR DKLQRRDAIS AIKKDVLESL AGRVASEGWS SAELSKEFGE
310 320 330 340 350
LEYHTMRDSV LETKVRIDGR ALDTVRPISV QAGVLPRTHG SALFTRGETQ
360 370 380 390 400
AIVVTTLGTA RDGQVIDAVA GEYKENFLFH YNFPPYSVGE CGRFGAPKRR
410 420 430 440 450
EIGHGRLAKR GVLAVMPSLE EFPYTIRVVS EITESNGSSS MASVCGSSLA
460 470 480 490 500
LMDAGVPVKA PVAGIAMGLV KEDDRFVVLS DILGDEDHLG DMDFKVAGTA
510 520 530 540 550
EGVSALQMDI KIEGITEEIM KQALQQAKAG RLHILGEMSK ALTTPRQELS
560 570 580 590 600
DYAPRLLTIK IHPDKIREVI GKGGSTIQAI TKETGTQIDI QDDGTIIIAS
610 620 630 640 650
VNAIAAQAAK SRIEQITSDV EPGRIYEGKV AKIMDFGAFV TILPGKDGLV
660 670 680 690 700
HVSQISSERV EKVGDKLKEG DLVRVKVLEV DKQGRIRLSI KAVEEGEGVP

ASAE
Length:704
Mass (Da):75,641
Last modified:September 1, 2009 - v2
Checksum:iC76AABE9E7D9D9DF
GO

Sequence cautioni

The sequence CAP51003 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM920689 Genomic DNA Translation: CAP51003.1 Different initiation.

Genome annotation databases

EnsemblBacteriaiCAP51003; CAP51003; xcc-b100_1653
KEGGixca:xcc-b100_1653

Similar proteinsi

Entry informationi

Entry nameiPNP_XANCB
AccessioniPrimary (citable) accession number: B0RRB8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: September 1, 2009
Last modified: May 23, 2018
This is version 68 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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