B0RNH1 (TREA_XANCB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Periplasmic trehalase
EC=3.2.1.28

Alternative name(s):
Alpha,alpha-trehalase
Alpha,alpha-trehalose glucohydrolase

Gene names

Name:	treA
Ordered Locus Names:	xcc-b100_0667

Organism

Xanthomonas campestris pv. campestris (strain B100) [Complete proteome] [HAMAP]

Taxonomic identifier

509169 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas

Protein attributes

Sequence length	568 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system By similarity. HAMAP MF_01060
Catalytic activity	Alpha,alpha-trehalose + H2O = 2 D-glucose. HAMAP MF_01060
Subcellular location	Periplasm By similarity HAMAP MF_01060.
Sequence similarities	Belongs to the glycosyl hydrolase 37 family.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Signal
Molecular function	Glycosidase Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular hyperosmotic response Inferred from electronic annotation. Source: InterPro trehalose catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	alpha,alpha-trehalase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 38	38	Potential
	Chain	39 – 568	530	Periplasmic trehalase HAMAP MF_01060		PRO_1000136428

Sequences

	Sequence		Length	Mass (Da)
	B0RNH1 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 29E4FA266074FF0A	FASTA	568	62,663
	10 20 30 40 50 60 MPHAPARSGD AMSAAAPPCC TSLLGLSLSM FVAPCALAAT PLEGAVVSAP APTPPTPDLA 70 80 90 100 110 120 YPELFQAVQR GELFDDQKHF VDFLPLRDPA LINADYLAQH EHAGFDLRKF VDANFEESPP 130 140 150 160 170 180 VQTDAIRQDT ALREHIDALW PKLVRSQTNV PAHSSLLALP HPYVVPGGRF REVYYWDSYF 190 200 210 220 230 240 TMLGLVKSGE TTLSRQMLDN FAYLIDTYGH IPNGNRTYYL SRSQPPFFSY MVELQAGVEG 250 260 270 280 290 300 EAVYQRYLPQ LQKEYAYWMQ GGDDLQPGQA ARHVVRLADG SVLNRYWDER DTPRPEAWLH 310 320 330 340 350 360 DTRTAAEAHD RPAADVYRDL RAGAESGWDY TSRWLADGKT LSTIRTTAIV PIDLNSLLYH 370 380 390 400 410 420 LERTLAQACA HTGTACSQDY AALAQQRKQA IDAHLWNAAG YYADYDWQTR TLSNQVTAAA 430 440 450 460 470 480 LYPLFAGLAS ADHAKRTATS VRARLLRPGG LATTALKTGQ QWDEPNGWAP LQWVAVDGLR 490 500 510 520 530 540 RYGEDGLART IGERFLTQVQ ALFAREHKLV EKYGLDADAA GGGGGEYALQ DGFGWTNGVT 550 560 LMLLNLYPSP GAIQAPAKTK RKPEPAAP

References

[1]

"The genome of Xanthomonas campestris pv. campestris B100 and its use for the reconstruction of metabolic pathways involved in xanthan biosynthesis." Vorhoelter F.-J., Schneiker S., Goesmann A., Krause L., Bekel T., Kaiser O., Linke B., Patschkowski T., Rueckert C., Schmid J., Sidhu V.K., Sieber V., Tauch A., Watt S.A., Weisshaar B., Becker A., Niehaus K., Puehler A. J. Biotechnol. 134:33-45(2008) [PubMed: 18304669] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: B100.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM920689 Genomic DNA. Translation: CAP50006.1.
RefSeq	YP_001902072.1. NC_010688.1.
3D structure databases
ProteinModelPortal	B0RNH1.
SMR	B0RNH1. Positions 54-549.
ModBase	Search...
Protein-protein interaction databases
STRING	B0RNH1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6321140.
GenomeReviews	Gene locus xcc-b100_0667 in contig AM920689_GR.
PATRIC	24081147. VBIXanCam108527_0685.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG485982.
OMA	NRYWDAS.
ProtClustDB	PRK13272.
Enzyme and pathway databases
BioCyc	XCAM487884:XCC-B100_0667-MONOMER.
Family and domain databases
HAMAP	MF_01060. Peripl_trehalase. [Tree]
InterPro	IPR008928. 6-hairpin_glycosidase-like. IPR001661. Glyco_hydro_37. IPR018232. Glyco_hydro_37_CS. IPR023720. Trehalase_periplasmic. [Graphical view]
PANTHER	PTHR23403. Glyco_hydro_37. 1 hit.
Pfam	PF01204. Trehalase. 1 hit. [Graphical view]
PRINTS	PR00744. GLHYDRLASE37.
SUPFAM	SSF48208. Glyco_trans_6hp. 1 hit.
PROSITE	PS00927. TREHALASE_1. 1 hit. PS00928. TREHALASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TREA_XANCB

Accession

Primary (citable) accession number: B0RNH1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	April 8, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program