Reviewed, UniProtKB/Swiss-Prot B0RIH2 (MQO_CLAMS)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	CMS0162

Organism

Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667) [Complete proteome] [HAMAP]

Taxonomic identifier

31964 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length	492 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 492	492	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000078031

Sequences

	Sequence		Length	Mass (Da)
	B0RIH2-1 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 0334A61EA15E32C4	FASTA	492	53,768
	10 20 30 40 50 60 MSDTAESVDV VLVGGGIMSA TLGTLIKQLE PDWTIQIFER LGEVAMESSN PWNNAGTGHA 70 80 90 100 110 120 ALCELNYTPE KDGKIEIGSA TRINEQFQLS RQFWAHLVTA GAVPEPKEFI NPTPHMTFVR 130 140 150 160 170 180 GKENAEYLRR RFDALRAHPL FDAMEYTEDP AVIHSWAPLL VLQRDKDEVI AATRFEGGTD 190 200 210 220 230 240 VDFGALTNKL VDYLMEHGAA LHLNHEVRGL SKNADGTWHL RVRNDVGRST VEVDAKFVFI 250 260 270 280 290 300 GAGGGALPLL QKSGIPEIKG FGGFPISGEW FRTDDPEIVA KHRAKVYGKA AIGSPPMSVP 310 320 330 340 350 360 HLDTRVVGGE TSLLFGPYAG FSPRFLKKGS LLDLFASIRP HNIIPMLAVA KDNMSLIKYL 370 380 390 400 410 420 VSQLLASKET KFDALREFMP TADPKDWYQV TAGQRVQVMK KDAEKGGVLQ FGTEVVAAAD 430 440 450 460 470 480 GSIAGLLGAS PGASTAVPIM LDVLERCFPD CIAGWKKPLT RMIPNYGTLV ASDPKKTPKI 490 IRETAEVLEL QH

References

[1]

"Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation." Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J., Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D., Parkhill J., Ishimaru C.A. J. Bacteriol. 190:2150-2160(2008) [PubMed: 18192393] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM849034 Genomic DNA. Translation: CAQ00286.1.
RefSeq	YP_001708950.1.
3D structure databases
SMR	B0RIH2. Positions 5-308.
ModBase	Search...
Genome annotation databases
GeneID	6156149.
GenomeReviews	Gene locus CMS0162 in contig AM849034_GR.
KEGG	cms:CMS_0162.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289663.
OMA	NTQFEVS.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_CLAMS

Accession

Primary (citable) accession number: B0RIH2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	April 8, 2008
Last modified:	February 9, 2010
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)