Reviewed, UniProtKB/Swiss-Prot B0RIG4 (ACKA_CLAMS)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	CMS0154

Organism

Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667) [Complete proteome] [HAMAP]

Taxonomic identifier

31964 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length	396 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 396	396	Acetate kinase HAMAP MF_00020		PRO_1000074182

Sequences

	Sequence		Length	Mass (Da)
	B0RIG4-1 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 089C8DB332A27D12	FASTA	396	42,037
	10 20 30 40 50 60 MPVVLVVNSG SSSFKYQLIE MDTETVLASG LVERIGEEVG STRHKAGGDS WERELPIADH 70 80 90 100 110 120 TAGFQAMLDA FADHGPSLEE GPPVAIGHRV VHGGDVFVEP TVVTEKVKAD IDDLSALAPL 130 140 150 160 170 180 HNPGALQGIQ AAQTAFPDVA HVAVFDTAFH QTLPAEAYTY AIDRELAAAH RIRRYGFHGT 190 200 210 220 230 240 SHKYVSEAAA RLLGKPLEET RIIVLHLGNG ASAAAVQGGR SIDTSMGLTP LEGLVMGTRS 250 260 270 280 290 300 GDIDPAILFH LARHTDLGLD DLETLLNRKS GLLGLTGLGD MRDVQRAAAD GDEDAQTALG 310 320 330 340 350 360 VYRHRIRHYV GAYAAQLGGV DAVVFTAGVG ENNPLVRRRS LAGLEFMGIG IDDDRNELIS 370 380 390 SEARFVSPDG SPVAVLVIPT DEELEIARQS LAATGN

References

[1]

"Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation." Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J., Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D., Parkhill J., Ishimaru C.A. J. Bacteriol. 190:2150-2160(2008) [PubMed: 18192393] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM849034 Genomic DNA. Translation: CAQ00278.1.
RefSeq	YP_001708942.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6156142.
GenomeReviews	Gene locus CMS0154 in contig AM849034_GR.
KEGG	cms:CMS_0154.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	SSDFRDV.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_CLAMS

Accession

Primary (citable) accession number: B0RIG4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	April 8, 2008
Last modified:	November 3, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)