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B0RIF1 (XYLA_CLAMS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Xylose isomerase
EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:CMS0141
OrganismClavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667) [Complete proteome] [HAMAP]
Taxonomic identifier31964 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_00455

Subunit structure

Homotetramer By similarity. HAMAP MF_00455

Subcellular location

Cytoplasm By similarity HAMAP MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

xylose isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Xylose isomerase HAMAP MF_00455
PRO_1000081027

Sites

Active site541 By similarity
Active site571 By similarity
Metal binding1811Magnesium 1 By similarity
Metal binding2171Magnesium 1 By similarity
Metal binding2171Magnesium 2 By similarity
Metal binding2201Magnesium 2 By similarity
Metal binding2451Magnesium 1 By similarity
Metal binding2551Magnesium 2 By similarity
Metal binding2571Magnesium 2 By similarity
Metal binding2931Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
B0RIF1 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 55519A4F010A393D

FASTA39743,748
        10         20         30         40         50         60 
MALTPTREDK FSFGLWTIGY TGADPFGGPT RSDLDVVEGV ERISELGAYG LTFHDDDLFA 

        70         80         90        100        110        120 
FGSTDAERQT QIDRLKGALS DTGIVVPMVT TNLFSAPVFK DGGFTSNDRA VRRFAIRKVL 

       130        140        150        160        170        180 
RNIDLAAELG AKTFVMWGGR EGAEYDSAKD VRGALERYRE AVNLLGDYVT DKGYDIRFAI 

       190        200        210        220        230        240 
EPKPNEPRGD ILLPTLGHAL AFIETLERPE LVGVNPEVGH EQMAGLNFTA GIMQALYQGK 

       250        260        270        280        290        300 
LFHIDLNGQR GIKYDQDLVF GHGDLQNAFS LVDLLENGGV GGGRSYDGPR HFDYKPSRTE 

       310        320        330        340        350        360 
DITGVWDSAA ANMRMYLLLK ERAQAFRADP EVQEALAAAK VAEIDTPTLN EGESYDDILA 

       370        380        390 
DRSSYEDFAA DEYFDAKGFG FVRLNQLALE HLMGARS

« Hide

References

[1]"Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation."
Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J., Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D., Parkhill J., Ishimaru C.A.
J. Bacteriol. 190:2150-2160(2008) [PubMed: 18192393] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33113 / JCM 9667.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM849034 Genomic DNA. Translation: CAQ00265.1.
RefSeqYP_001708929.1. NC_010407.1.

3D structure databases

ProteinModelPortalB0RIF1.
SMRB0RIF1. Positions 6-396.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0RIF1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6156130.
GenomeReviewsGene locus CMS0141 in contig AM849034_GR.
KEGGcms:CMS_0141.
PATRIC21457230. VBIClaMic4666_0191.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG322444.
OMAPKPNEPR.
ProtClustDBPRK12677.

Enzyme and pathway databases

BioCycCMIC31964:CMS0141-MONOMER.

Family and domain databases

HAMAPMF_00455. Xylose_isom_A.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01805.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR02631. XylA_Arthro. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_CLAMS
AccessionPrimary (citable) accession number: B0RIF1
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 8, 2008
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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