B0RG25 (B0RG25_CLAMS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase HAMAP MF_00259
EC=2.1.2.10 HAMAP MF_00259

Alternative name(s):
Glycine cleavage system T protein HAMAP MF_00259

Gene names

Name:	gcvT HAMAP MF_00259
Ordered Locus Names:	CMS2224

Organism

Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667) [Complete proteome] [HAMAP] EMBL CAQ02316.1

Taxonomic identifier

31964 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259

Ontologies

Keywords
Molecular function	Aminotransferase HAMAP MF_00259 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0RG25 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: B7FC9480072315A6	FASTA	399	41,539
	10 20 30 40 50 60 MTDAPAPDPE VRRSPLHAVH EAAGASFTDF AGWLMPVRYT SDLAEHRAVR EAAGIFDISH 70 80 90 100 110 120 MAEIAVEGEG AAAFLDSVLA GKLSAIAEWQ AKYTLLLDPS GGIVDDLIVY RTGEESFLVV 130 140 150 160 170 180 ANAGNHDPVI AVLAEAAEGL DDVEVDDASD DVALIAVQGP VSRAILEATA GLETESPLEA 190 200 210 220 230 240 LRYYRATAAR FAGQDVLVAR TGYTGEDGYE LYVATEDAVA LWEALVAAGT PLGLLPTGLA 250 260 270 280 290 300 CRDTLRLEAG MPLYGHELGL HTLPGQAGLG KVVALAKEGD FRGRAAVEKG PDPVARVLVG 310 320 330 340 350 360 LVTEGRRAPR ADYPVYAEEA AGDSAAALEA VMEATEGAVP PVGIVTSGAL SPTLGHPVAM 370 380 390 AYVDPSLAAP GTRLAVDVRG TRVPATVVTL PFYSRKAIR

References

[1]

"Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation." Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J., Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D., Parkhill J., Ishimaru C.A. J. Bacteriol. 190:2150-2160(2008) [PubMed: 18192393] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM849034 Genomic DNA. Translation: CAQ02316.1.
RefSeq	YP_001710900.1. NC_010407.1.
3D structure databases
ProteinModelPortal	B0RG25.
ModBase	Search...
Protein-protein interaction databases
STRING	B0RG25.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6158713.
GenomeReviews	Gene locus CMS2224 in contig AM849034_GR.
KEGG	cms:CMS_2224.
PATRIC	21461503. VBIClaMic4666_2295.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG299834.
OMA	KALYGGM.
ProtClustDB	CLSK2325392.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0RG25_CLAMS

Accession

Primary (citable) accession number: B0RG25

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)