B0RG04 (B0RG04_CLAMS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase HAMAP MF_00137
EC=6.3.2.6 HAMAP MF_00137

Alternative name(s):
SAICAR synthetase HAMAP MF_00137

Gene names

Name:	purC HAMAP MF_00137
Ordered Locus Names:	CMS1027

Organism

Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667) [Complete proteome] [HAMAP] EMBL CAQ01141.1

Taxonomic identifier

31964 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length	306 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. HAMAP MF_00137
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. HAMAP MF_00137
Sequence similarities	Belongs to the SAICAR synthetase family. HAMAP MF_00137

Ontologies

Keywords
Biological process	Purine biosynthesis HAMAP MF_00137
Ligand	ATP-binding HAMAP MF_00137 Nucleotide-binding
Molecular function	Ligase HAMAP MF_00137 EMBL CAQ01141.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine nucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0RG04 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 4A768666E0A037DF	FASTA	306	34,022
	10 20 30 40 50 60 MSAQAPAGHA SEWDLPGWDH AYSGKVRELF SPAVDDTDDR ALEGEPHVLV VATDRVSAYD 70 80 90 100 110 120 FALEPGIPGK GELLTQLSLW WFDRLEVPNH LVDAATLDRI GIPESVQGRA MLCRVLEMLP 130 140 150 160 170 180 IECVVRGYLA GSGWEEYREH GTVCGIPLPA GLQQGDRLPE PIYTPAWKAP QGEHDENITF 190 200 210 220 230 240 ARTEELVGHE EAARLRDLSL DVYRRAAAIA EERGVILADT KFEFGIDPRT GITTLADEVL 250 260 270 280 290 300 TSDSSRYWDA EAHATGNRTD SFDKQIVRDW LAANWDRTGT PPVLPQEIVE RTAGRYRELI ARLTGR

References

[1]

"Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation." Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J., Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D., Parkhill J., Ishimaru C.A. J. Bacteriol. 190:2150-2160(2008) [PubMed: 18192393] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM849034 Genomic DNA. Translation: CAQ01141.1.
RefSeq	YP_001709770.1. NC_010407.1.
3D structure databases
ProteinModelPortal	B0RG04.
ModBase	Search...
Protein-protein interaction databases
STRING	B0RG04.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6156929.
GenomeReviews	Gene locus CMS1027 in contig AM849034_GR.
KEGG	cms:CMS_1027.
PATRIC	21459064. VBIClaMic4666_1093.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG555040.
OMA	LTLMDEV.
ProtClustDB	PRK13961.
Family and domain databases
HAMAP	MF_00137. SAICAR_synth. [Tree]
InterPro	IPR013816. ATP_grasp_subdomain_2. IPR001636. SAICAR_synth. IPR018236. SAICAR_synthetase_CS. [Graphical view]
Gene3D	G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
KO	K01923.
PANTHER	PTHR11609. SAICAR_synt. 1 hit.
Pfam	PF01259. SAICAR_synt. 1 hit. [Graphical view]
TIGRFAMs	TIGR00081. PurC. 1 hit.
PROSITE	PS01057. SAICAR_SYNTHETASE_1. 1 hit. PS01058. SAICAR_SYNTHETASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B0RG04_CLAMS

Accession

Primary (citable) accession number: B0RG04

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)