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B0RF18 (B0RF18_CLAMS) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length335 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain135 – 327193ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding161 – 21252ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2811Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2941Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2941Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2961Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
B0RF18 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 15182CD4087C75FE

FASTA33534,310
        10         20         30         40         50         60 
MRISVLFGGE SEERDVSIAS AAQVVPALRQ LGHEVVAVDT AHGALDAAAE ARILTPDVGL 

        70         80         90        100        110        120 
HPPTSAELAT ASAGGSGAVL RLPADLRDSD LVFLALHGGS GEDGRLQALL ELAGIPFTGS 

       130        140        150        160        170        180 
GSLGSALAMD KDVAKTLLRA GGVRTPDWLI DPEPGAVEAA LGFPVVVKPT GQGSTVGLSV 

       190        200        210        220        230        240 
VRAAADLPAA LELAARHGTV MVERFVRGRE LTVGVLDGEA LAVGEIGVPV DEAFTYAAKY 

       250        260        270        280        290        300 
QAGAIAETFP ADLPSEVAEE ARAAALAAHR ILRLDGYSRS DFRLDDAGIL WIIEANSLPG 

       310        320        330 
LTATSLLPQS AAAVGIGYAE LCERIARVVL RGRAG 

« Hide

References

[1]"Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation."
Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J., Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D., Parkhill J., Ishimaru C.A.
J. Bacteriol. 190:2150-2160(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM849034 Genomic DNA. Translation: CAQ00951.1.
RefSeqYP_001709590.1. NC_010407.1.

3D structure databases

ProteinModelPortalB0RF18.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING31964.CMS_0834.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAQ00951; CAQ00951; CMS0834.
GeneID6156749.
KEGGcms:CMS_0834.
PATRIC21458662. VBIClaMic4666_0892.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
KOK01921.
OMAGELQAMC.
OrthoDBEOG6ND0KB.
ProtClustDBCLSK868521.

Enzyme and pathway databases

BioCycCMIC31964:GJBN-843-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0RF18_CLAMS
AccessionPrimary (citable) accession number: B0RF18
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: February 19, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)