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B0REW2 (B0REW2_CLAMS) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Dihydroorotase EMBL CAQ02128.1
EC=3.5.2.3 EMBL CAQ02128.1
Gene names
Name:pyrC EMBL CAQ02128.1
Ordered Locus Names:CMS2032
OrganismClavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667) [Complete proteome] [HAMAP] EMBL CAQ02128.1
Taxonomic identifier31964 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length463 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. SAAS SAAS002195

Cofactor

Binds 2 zinc ions per subunit By similarity. SAAS SAAS002195

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. SAAS SAAS002195

Subunit structure

Homodimer By similarity. SAAS SAAS002195

Sequences

Sequence LengthMass (Da)Tools
B0REW2 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 709CBC2B795D6BC6

FASTA46348,226
        10         20         30         40         50         60 
MTQNDTHLIR GATLPSGERA DILVADGLIR EIGPDLDAPA GAHVVGADGL VALPGLVDLH 

        70         80         90        100        110        120 
VHLREPGYEQ SETVLTGSRA AALGGFTAVF AMANTMPVQD TAGVVEQVKA LGDAAGYATV 

       130        140        150        160        170        180 
RPIGAVSVGL AGESMAEIGA MASSRAAVRV FSDDGKCVSD PLLMRRALEY VKAFDGVIAQ 

       190        200        210        220        230        240 
HAQDPRLTEG ATMNEGALSG ELGITGWPAV AEESIIARDV LLAEHVGSRL HVCHVSTAGS 

       250        260        270        280        290        300 
VDVIRWAKAR GVDVTAEVTP HHLLLTEDLV AGYDARYKVN PPLRRREDVE ALRTALADGT 

       310        320        330        340        350        360 
IDVVATDHAP HPTEAKDCEW DAAAFGMVGL ESALSVVQLA MVDTGLLDWA GVARVMSHAP 

       370        380        390        400        410        420 
ARIGRLAEHG HALAGGSPAD ITLYDPSASR VFGRDDLGGL SGNSPYLEMT LPGRVVATFH 

       430        440        450        460 
RGYPTVLDGA LVDRETVARA AVLRDRADAD ARDAAVATRG SGA

« Hide

References

[1]"Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation."
Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J., Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D., Parkhill J., Ishimaru C.A.
J. Bacteriol. 190:2150-2160(2008) [PubMed: 18192393] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM849034 Genomic DNA. Translation: CAQ02128.1.
RefSeqYP_001710723.1. NC_010407.1.

3D structure databases

ProteinModelPortalB0REW2.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0REW2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6157698.
GenomeReviewsGene locus CMS2032 in contig AM849034_GR.
KEGGcms:CMS_2032.
PATRIC21461103. VBIClaMic4666_2095.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG724623.
OMACDVHPVG.
ProtClustDBPRK09357.

Family and domain databases

HAMAPMF_00220_B. PyrC_type2_B.
[Tree]
InterProIPR006680. Amidohydro_1.
IPR004722. DHOase.
IPR002195. Dihydroorotase_CS.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
KOK01465.
PfamPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMSSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMsTIGR00857. PyrC_multi. 1 hit.
PROSITEPS00482. DIHYDROOROTASE_1. 1 hit.
PS00483. DIHYDROOROTASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0REW2_CLAMS
AccessionPrimary (citable) accession number: B0REW2
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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