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B0RD41

- B0RD41_CLAMS

UniProt

B0RD41 - B0RD41_CLAMS

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Protein

Alanine racemase

Gene

alr*

Organism
Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1) (Corynebacterium sepedonicum)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei48 – 481Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei146 – 1461SubstrateUniRule annotation
Active sitei276 – 2761Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei324 – 3241Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
  2. threonylcarbamoyladenosine biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCMIC31964:GJBN-529-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alr*Imported
Ordered Locus Names:CMS0521Imported
OrganismiClavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1) (Corynebacterium sepedonicum)Imported
Taxonomic identifieri31964 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrobacteriaceaeClavibacter
ProteomesiUP000001318: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei48 – 481N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi31964.CMS_0521.

Structurei

3D structure databases

ProteinModelPortaliB0RD41.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0802.
KOiK01775.
OMAiIYSHLAL.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR027417. P-loop_NTPase.
IPR029066. PLP-binding_barrel.
IPR003442. T6A_TsaE.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
PF02367. UPF0079. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
TIGR00150. T6A_YjeE. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B0RD41-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTEPASAPAS AGPVAPGRRA VIDLDAIRHN VRTLAALAAP ARTMVAVKAD
60 70 80 90 100
AYGHGALQVA RAALESGAES LAVLDVASAV ELRRAGIDAR LLAWLHGVDT
110 120 130 140 150
DFRVAVEEEI DLGVSALWEL KRIAAAGRAT GIRARVHLKA DTGLSRNGAT
160 170 180 190 200
PELWPDLVRA AVAADSAGEL TLHALWSHLA DASPEDDDAA LARFREAVRV
210 220 230 240 250
AEELGARPVE KHLAASSAGI RLPAARFDMV RFGIAVYGIS PFDDRSGRDL
260 270 280 290 300
GLIPAMTLEA DVVSVKRVEA GHGVSYGLDH RTAGPSTLVL VPLGYADGIP
310 320 330 340 350
RIAAPRASVL LNGRRFPVAG RIAMDQLVLD VGDLPVEVGD TAVILGPGDR
360 370 380 390 400
GEPTAEEWAG WAETIGDEIV TRVGPRVDRV HLHERADADD PDGGGAAANG
410 420 430 440 450
ATAEVLSDEL VPVATTDDME ELGRAVAREL GAGDLVVLSG PLGAGKTTFT
460 470 480 490 500
RGLGAGLGVR GPVTSPTFVL ARTHPSLVDG PPLVHVDAYR LADARELDDL
510 520 530 540 550
DIDFARSVVV VEWGEGKLDG VAEEWWELAI ARPTGAGDAD PDAADGGHDG
560 570
AHDASDPDAA PEEPRTVRIR RLRARPRA
Length:578
Mass (Da):60,399
Last modified:April 8, 2008 - v1
Checksum:iC9CA589B45C5123E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM849034 Genomic DNA. Translation: CAQ00640.1.
RefSeqiYP_001709292.1. NC_010407.1.

Genome annotation databases

EnsemblBacteriaiCAQ00640; CAQ00640; CMS0521.
GeneIDi6158594.
KEGGicms:CMS_0521.
PATRICi21458023. VBIClaMic4666_0580.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM849034 Genomic DNA. Translation: CAQ00640.1 .
RefSeqi YP_001709292.1. NC_010407.1.

3D structure databases

ProteinModelPortali B0RD41.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 31964.CMS_0521.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAQ00640 ; CAQ00640 ; CMS0521 .
GeneIDi 6158594.
KEGGi cms:CMS_0521.
PATRICi 21458023. VBIClaMic4666_0580.

Phylogenomic databases

eggNOGi COG0802.
KOi K01775.
OMAi IYSHLAL.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci CMIC31964:GJBN-529-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR027417. P-loop_NTPase.
IPR029066. PLP-binding_barrel.
IPR003442. T6A_TsaE.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
PF02367. UPF0079. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
TIGR00150. T6A_YjeE. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation."
    Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J., Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D., Parkhill J., Ishimaru C.A.
    J. Bacteriol. 190:2150-2160(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1Imported.

Entry informationi

Entry nameiB0RD41_CLAMS
AccessioniPrimary (citable) accession number: B0RD41
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3