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B0RD40

- B0RD40_CLAMS

UniProt

B0RD40 - B0RD40_CLAMS

Protein

Alanine racemase

Gene

alr

Organism
Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1) (Corynebacterium sepedonicum)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei45 – 451Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei143 – 1431SubstrateUniRule annotation
    Active sitei273 – 2731Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei321 – 3211Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciCMIC31964:GJBN-528-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    Ordered Locus Names:CMS0520Imported
    OrganismiClavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1) (Corynebacterium sepedonicum)Imported
    Taxonomic identifieri31964 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrobacteriaceaeClavibacter
    ProteomesiUP000001318: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei45 – 451N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi31964.CMS_0520.

    Structurei

    3D structure databases

    ProteinModelPortaliB0RD40.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    KOiK01775.
    OMAiPSECAGV.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B0RD40-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTDEATVQVP AALRREARID LGAISTNVRT LRAAAGAPLV MAVVKADGYG    50
    HGAVASARAA LAGGADRLGV VDIREALALR AAGIEAPILT WMHAPYADFA 100
    TAIEAGIDLG LNSLRQVREA AEAARRVGRT AEVHLKVDTG LGRNGVTPAE 150
    WPGVVAEVAA LVAEGRIHLG GVFSHLANAG EDEDRAQVRA FHEAVDVVRA 200
    AGLEPGIRHL AATAGALRVP EARLDMVRLG IGIYGISPLD GVTSADLGLV 250
    PAMTLVGSVV AVKRVPADTG VSYGYTYRTT SATTLALVSL GFADGVPRLA 300
    SNRAPVAIHG ARFRVSGRIA MDQFVVDVGD GVVDGRPVAV GDDAVLFGDP 350
    ATGAPSVEEW AEATGTIGYE IVARVAGRVT RRHSA 385
    Length:385
    Mass (Da):39,664
    Last modified:April 8, 2008 - v1
    Checksum:i989F4D16F3258B92
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM849034 Genomic DNA. Translation: CAQ00639.1.
    RefSeqiWP_012297964.1. NC_010407.1.
    YP_001709291.1. NC_010407.1.

    Genome annotation databases

    EnsemblBacteriaiCAQ00639; CAQ00639; CMS0520.
    GeneIDi6158590.
    KEGGicms:CMS_0520.
    PATRICi21458021. VBIClaMic4666_0579.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM849034 Genomic DNA. Translation: CAQ00639.1 .
    RefSeqi WP_012297964.1. NC_010407.1.
    YP_001709291.1. NC_010407.1.

    3D structure databases

    ProteinModelPortali B0RD40.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 31964.CMS_0520.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAQ00639 ; CAQ00639 ; CMS0520 .
    GeneIDi 6158590.
    KEGGi cms:CMS_0520.
    PATRICi 21458021. VBIClaMic4666_0579.

    Phylogenomic databases

    eggNOGi COG0787.
    KOi K01775.
    OMAi PSECAGV.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci CMIC31964:GJBN-528-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation."
      Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J., Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D., Parkhill J., Ishimaru C.A.
      J. Bacteriol. 190:2150-2160(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1Imported.

    Entry informationi

    Entry nameiB0RD40_CLAMS
    AccessioniPrimary (citable) accession number: B0RD40
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 8, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3