Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Dihydrolipoyl dehydrogenase

Gene

pdhD

Organism
Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1) (Corynebacterium sepedonicum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Miscellaneous

The active site is a redox-active disulfide bond.UniRule annotation

Catalytic activityi

Protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH.UniRule annotation

Cofactori

FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandFADUniRule annotation, Flavoprotein, NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoyl dehydrogenaseUniRule annotation (EC:1.8.1.4UniRule annotation)
Gene namesi
Name:pdhDImported
Ordered Locus Names:CMS1625Imported
ORF Names:B5P19_03315Imported, B5P20_01575Imported
OrganismiClavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1) (Corynebacterium sepedonicum)Imported
Taxonomic identifieri31964 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrobacteriaceaeClavibacter
Proteomesi
  • UP000001318 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi31964.CMS_1625.

Structurei

3D structure databases

ProteinModelPortaliB0RC07.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 317FAD/NAD-binding_domInterPro annotationAdd BLAST312
Domaini337 – 445Pyr_redox_dimInterPro annotationAdd BLAST109

Sequence similaritiesi

Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.UniRule annotation

Keywords - Domaini

Redox-active centerUniRule annotation

Phylogenomic databases

eggNOGiENOG4107QN2. Bacteria.
COG1249. LUCA.
KOiK00382.
OMAiCIDEWKN.
OrthoDBiPOG091H0239.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 1 hit.
InterProiView protein in InterPro
IPR036188. FAD/NAD-bd_sf.
IPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer_sf.
IPR006258. Lipoamide_DH.
IPR001100. Pyr_nuc-diS_OxRdtase.
IPR004099. Pyr_nucl-diS_OxRdtase_dimer.
IPR012999. Pyr_OxRdtase_I_AS.
PfamiView protein in Pfam
PF07992. Pyr_redox_2. 1 hit.
PF02852. Pyr_redox_dim. 1 hit.
PIRSFiPIRSF000350. Mercury_reductase_MerA. 1 hit.
SUPFAMiSSF51905. SSF51905. 1 hit.
SSF55424. SSF55424. 1 hit.
TIGRFAMsiTIGR01350. lipoamide_DH. 1 hit.
PROSITEiView protein in PROSITE
PS00076. PYRIDINE_REDOX_1. 1 hit.

Sequencei

Sequence statusi: Complete.

B0RC07-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEQNFDVVV LGGGSGGYAA ALRAVQLGKT VGLVEKGKLG GTCLHRGCIP
60 70 80 90 100
TKALLHSAEV ADVSRESEKY GVIATFDGVD IAKVNAYREA IVASKYKGLQ
110 120 130 140 150
GLIKARGITV IEGEGRLTSG TTVQVGDQTI TGKSVVLATG SYSRTLPGLE
160 170 180 190 200
IGGCVITSEQ ALELDYIPKK VAILGGGVIG VEFASVWRSF GVEVQIVEAL
210 220 230 240 250
PHLVPNEEES ISKQFERAFR KRGIAFSLGV RFKSVMQHDQ GVQVALEDGT
260 270 280 290 300
TYDADLLLVA VGRGPATQGL GFEEAGVKTD RGFVLTDERL QTSVPGVYAV
310 320 330 340 350
GDIVPGLQLA HRGFQQGIFV AEEIAGNKPV VVEDINIPKV TYSDPEVASV
360 370 380 390 400
GYSEAKAVEK FGADKVSSYE YNLGGNGKSS ILGTAGSIKV VRVQDGPVVG
410 420 430 440 450
IHMIGVRVGE LIGEGQLIVN WEAYPEDVAN LVHAHPTQNE ALGEAHLALA

GTPLHAL
Length:457
Mass (Da):48,056
Last modified:April 8, 2008 - v1
Checksum:i60CE0283E3AB796E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM849034 Genomic DNA. Translation: CAQ01735.1.
MZMM01000001 Genomic DNA. Translation: OQJ47413.1.
MZMN01000003 Genomic DNA. Translation: OQJ52968.1.
RefSeqiWP_012298991.1. NZ_MZMN01000003.1.

Genome annotation databases

EnsemblBacteriaiCAQ01735; CAQ01735; CMS1625.
GeneIDi29469944.
KEGGicms:CMS1625.

Similar proteinsi

Entry informationi

Entry nameiB0RC07_CLAMS
AccessioniPrimary (citable) accession number: B0RC07
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: November 22, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported