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B0RBL7 (B0RBL7_CLAMS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:CMS2842
OrganismClavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667) [Complete proteome] [HAMAP] EMBL CAQ02913.1
Taxonomic identifier31964 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length384 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323

Ontologies

Keywords
   Biological processHeme biosynthesis HAMAP MF_00323
Porphyrin biosynthesis HAMAP MF_00323
   Cellular componentCytoplasm HAMAP MF_00323
   LigandIron HAMAP MF_00323
Metal-binding HAMAP MF_00323
   Molecular functionLyase HAMAP MF_00323 EMBL CAQ02913.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processheme biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionferrochelatase activity

Inferred from electronic annotation. Source: HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2001Iron By similarity HAMAP MF_00323
Metal binding2981Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
B0RBL7 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 5E67DF3466BB1B68

FASTA38442,280
        10         20         30         40         50         60 
MGPAHVEEPV AYDAILLASF GGPEGQDDVI PFLRNVTAGR GIPEERLEEV AHHYRAFGGI 

        70         80         90        100        110        120 
SPINEQNREL KAALEARLAE RGIDLPVLWG NRNWGPYLND ALREAEEKGY RQLIAVATSA 

       130        140        150        160        170        180 
YSSYSSCRQY REDFADALED TQLQGVIRID KVRQFFDHPG FVTPFIEGTR DGIRDVIAHF 

       190        200        210        220        230        240 
EAEGKPVDLA TDVEILFSTH SIPSSDASKS GPAERGFDQD GAYAAQHLAV AEVVMHEVRK 

       250        260        270        280        290        300 
ELGIDQDVPW QLVYQSRSGP PSMPWLEPDV NDAIGELPAQ GRRAVVIVPL GFVSDHMEVK 

       310        320        330        340        350        360 
WDLDNEATES AAENGLYSVR VPTPGVHAAY VDGLIDLVLE RRDGMKAADR PHMTDLGPWY 

       370        380 
DVCRPGCCEN VRLGFKPAVS GLAP

« Hide

References

[1]"Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation."
Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J., Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D., Parkhill J., Ishimaru C.A.
J. Bacteriol. 190:2150-2160(2008) [PubMed: 18192393] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM849034 Genomic DNA. Translation: CAQ02913.1.
RefSeqYP_001711475.1. NC_010407.1.

3D structure databases

ProteinModelPortalB0RBL7.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0RBL7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6158743.
GenomeReviewsGene locus CMS2842 in contig AM849034_GR.
KEGGcms:CMS_2842.
PATRIC21462721. VBIClaMic4666_2895.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697135.
OMAPAVVMAP.
ProtClustDBPRK00035.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0RBL7_CLAMS
AccessionPrimary (citable) accession number: B0RBL7
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info