B0RB78 (GLMM_CLAMS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	CMS0322

Organism

Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM 9667) [Complete proteome] [HAMAP]

Taxonomic identifier

31964 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length	449 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 449	449	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_1000087760
Sites
	Active site	105	1	Phosphoserine intermediate By similarity
	Metal binding	105	1	Magnesium; via phosphate group By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
	Metal binding	246	1	Magnesium By similarity
Amino acid modifications
	Modified residue	105	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B0RB78 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: C1A6EEE7F0A17900	FASTA	449	46,957
	10 20 30 40 50 60 MPRLFGTDGV RGLANGETIT ADLALRLAQA AAHVLGQDAR DAGRRPVAVV ARDPRVSGEF 70 80 90 100 110 120 IAAAVAAGLA SSGVDVFDAG VIPTPATAYL IADFDADFGV MISASHNPAP DNGIKFFAAG 130 140 150 160 170 180 GRKLADELED RIEAQLSQPV LLPTGADVGR IRRFADAEDR YVLHLLGTLQ HRLDGIHVVL 190 200 210 220 230 240 DCAHGAAAGI SPEVSTDAGA RVTVIGNDPD GMNINDRVGS THLDLLAEAV LGHGADVGIA 250 260 270 280 290 300 YDGDADRCLA VDHTGAIIDG DQIMAVLALS MARRGLLVER TLVATVMSNL GLRIAMAEND 310 320 330 340 350 360 ITVLQTRVGD RYVLEAMNEG GYSLGGEQSG HLVIAEHATT GDGILTGIQL LGEMAATGRS 370 380 390 400 410 420 LHELASVMTV YPQVMINVRG VDRERVSDDA ELNAAVARAE AELGDTGRIL MRASGTEPMI 430 440 RVMVEAADQA TAERHAQELA ALVTERLAI

References

[1]

"Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation." Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J., Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D., Parkhill J., Ishimaru C.A. J. Bacteriol. 190:2150-2160(2008) [PubMed: 18192393] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33113 / JCM 9667.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM849034 Genomic DNA. Translation: CAQ00443.1.
RefSeq	YP_001709104.1. NC_010407.1.
3D structure databases
ProteinModelPortal	B0RB78.
ModBase	Search...
Protein-protein interaction databases
STRING	B0RB78.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6156293.
GenomeReviews	Gene locus CMS0322 in contig AM849034_GR.
KEGG	cms:CMS_0322.
PATRIC	21457618. VBIClaMic4666_0382.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG644964.
OMA	GVGSTHL.
ProtClustDB	PRK14318.
Enzyme and pathway databases
BioCyc	CMIC31964:CMS0322-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 2 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_CLAMS

Accession

Primary (citable) accession number: B0RB78

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	April 8, 2008
Last modified:	January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program