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B0R9W9 (B0R9W9_HALS3) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aspartate carbamoyltransferase HAMAP MF_00001
EC=2.1.3.2 HAMAP MF_00001
Alternative name(s):
Aspartate transcarbamylase HAMAP MF_00001
Gene names
Name:pyrB HAMAP MF_00001 EMBL CAP15550.1
Ordered Locus Names:OE5201F
Encoded onPlasmid PHS3 EMBL CAP15550.1
OrganismHalobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) [Complete proteome] [HAMAP]
Taxonomic identifier478009 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium

Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate. HAMAP MF_00001

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3. HAMAP MF_00001

Subunit structure

Heterooligomer of catalytic and regulatory chains By similarity. HAMAP MF_00001

Sequence similarities

Belongs to the ATCase/OTCase family. HAMAP MF_00001 RuleBase RU003634

Sequences

Sequence LengthMass (Da)Tools
B0R9W9 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: CFBFB4CEBD52749D

FASTA31034,396
        10         20         30         40         50         60 
MDLDHIITSK QLSRADIETV LDRAAEIDAD PSAFADRYEN TVLGLLFFEP STRTKMSFDT 

        70         80         90        100        110        120 
AMKRLGGDIV DMGSVDSSSV KKGETLADTV RVIEGYADAL VLRHPNQGAA QMASEFVDVP 

       130        140        150        160        170        180 
LLNAGDGAGH HPTQTLLDLY TIRENAGLED LTIGIMGDLK YGRTVHSLSR ALTNFDVDQH 

       190        200        210        220        230        240 
FISPESLQLP RDVVYDLEQE SGTRVREHDS FEDVLPELDI LYVTRIQRER FPDENEYQKV 

       250        260        270        280        290        300 
AGEYQLTATH LEAAKDDLTI MHPLPRVDEI APEIDDTDHA AYFEQAHNGV PVRMALLDLV 

       310 
LSADGGVDDE

« Hide

References

[1]"Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1."
Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K., Ruepp A., Soppa J., Tittor J., Oesterhelt D.
Genomics 91:335-346(2008) [PubMed: 18313895] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29341 / DSM 671 / R1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM774418 Genomic DNA. Translation: CAP15550.1.
RefSeqYP_001690683.1. NC_010368.1.

3D structure databases

ProteinModelPortalB0R9W9.
SMRB0R9W9. Positions 4-303.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0R9W9.

Proteomic databases

PRIDEB0R9W9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5954945.
GenomeReviewsGene locus OE5201F in contig AM774418_GR.
KEGGhsl:OE5201F.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG579429.
OMAADRYENT.
PhylomeDBB0R9W9.
ProtClustDBPRK00856.

Family and domain databases

HAMAPMF_00001. Asp_carb_tr.
[Tree]
InterProIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002082. Asp_carbamoyltransf_euk.
[Graphical view]
KOK00609.
PfamPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSPR00100. AOTCASE.
PR00101. ATCASE.
SUPFAMSSF53671. Asp/Orn_carbamoyltranf. 1 hit.
TIGRFAMsTIGR00670. Asp_carb_tr. 1 hit.
PROSITEPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0R9W9_HALS3
AccessionPrimary (citable) accession number: B0R9W9
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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