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Protein

Probable thymidylate kinase

Gene

tmk

Organism
Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + dTMP = ADP + dTDP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi7 – 148ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Nucleotide biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHSAL478009:GJVF-1565-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable thymidylate kinaseUniRule annotation (EC:2.7.4.9UniRule annotation)
Alternative name(s):
dTMP kinaseUniRule annotation
Gene namesi
Name:tmkUniRule annotation
Ordered Locus Names:OE_3715R
OrganismiHalobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
Taxonomic identifieri478009 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
Proteomesi
  • UP000001321 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 199199Probable thymidylate kinasePRO_1000097400Add
BLAST

Proteomic databases

PRIDEiB0R6P3.

Structurei

3D structure databases

ProteinModelPortaliB0R6P3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidylate kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229077.
KOiK00943.
OMAiYTADHAA.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00165. Thymidylate_kinase. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR018094. Thymidylate_kinase.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00041. DTMP_kinase. 1 hit.

Sequencei

Sequence statusi: Complete.

B0R6P3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVTLEGLDG SGKTTVWESL RASHDDGVTF TAEPTDSQYG QAVRRSESAA
60 70 80 90 100
DADPIAELFL FTADHADHLS RVVSPALDRG DVVISDRYSD SRYAYQGATL
110 120 130 140 150
ADTVPRAMEY VRGIHQPWTR PPDVTLYFDV DPDTGAARSG ATNKFETAAF
160 170 180 190
LADVRANYEQ LIDYTPERFV RIDATQSPEA VIADAEAALA DALPDDAWA
Length:199
Mass (Da):21,688
Last modified:April 8, 2008 - v1
Checksum:i4C877D1C8B0D9FE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM774415 Genomic DNA. Translation: CAP14412.1.
RefSeqiWP_010903416.1. NC_010364.1.

Genome annotation databases

EnsemblBacteriaiCAP14412; CAP14412; OE_3715R.
GeneIDi5953168.
KEGGihsl:OE_3715R.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM774415 Genomic DNA. Translation: CAP14412.1.
RefSeqiWP_010903416.1. NC_010364.1.

3D structure databases

ProteinModelPortaliB0R6P3.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB0R6P3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAP14412; CAP14412; OE_3715R.
GeneIDi5953168.
KEGGihsl:OE_3715R.

Phylogenomic databases

HOGENOMiHOG000229077.
KOiK00943.
OMAiYTADHAA.

Enzyme and pathway databases

BioCyciHSAL478009:GJVF-1565-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00165. Thymidylate_kinase. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR018094. Thymidylate_kinase.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00041. DTMP_kinase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiKTHY_HALS3
AccessioniPrimary (citable) accession number: B0R6P3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: September 7, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.