B0R685 (KCY_HALS3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	OE3429F

Organism

Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) [Complete proteome] [HAMAP]

Taxonomic identifier

478009 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium

Protein attributes

Sequence length	192 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00239
Subcellular location	Cytoplasm By similarity HAMAP MF_00239.
Sequence similarities	Belongs to the cytidylate kinase family. Type 2 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 192	192	Cytidylate kinase HAMAP MF_00239		PRO_1000100708
Regions
	Nucleotide binding	7 – 15	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	B0R685 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 4BEC104FDFC0AB85	FASTA	192	21,632
	10 20 30 40 50 60 MLVTISGPPG SGKSTVASTL ADHLSYEHIS GGDIFRGLAE DRDLTLAEFN ELAEEDPQID 70 80 90 100 110 120 KDLDRRLRET ARGRDDIVLE SRLAGWMAGE YADIKIWLDA PMSVRARRIA EREDKTPAAA 130 140 150 160 170 180 RAETEAREES ETQRYEEYYA IDFDDITIYD LSVNTARWGP DAVTDIVLDA VDAYQAERDE 190 GPTPIENVRY QF

References

[1]

"Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1." Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K., Ruepp A., Soppa J., Tittor J., Oesterhelt D. Genomics 91:335-346(2008) [PubMed: 18313895] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29341 / DSM 671 / R1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM774415 Genomic DNA. Translation: CAP14254.1.
RefSeq	YP_001689600.1. NC_010364.1.
3D structure databases
ProteinModelPortal	B0R685.
ModBase	Search...
Protein-protein interaction databases
STRING	B0R685.
Proteomic databases
PRIDE	B0R685.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5953084.
GenomeReviews	Gene locus OE3429F in contig AM774415_GR.
KEGG	hsl:OE3429F.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG578180.
OMA	CAGFIFR.
PhylomeDB	B0R685.
ProtClustDB	PRK04182.
Enzyme and pathway databases
BioCyc	HSAL478009:OE3429F-MONOMER.
Family and domain databases
HAMAP	MF_00239. Cytidyl_kinase_type2. [Tree]
InterPro	IPR000850. Adenylate_kin. IPR011892. Cyt_kin_arch. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
Pfam	PF00406. ADK. 1 hit. PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR02173. Cyt_kin_arch. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_HALS3

Accession

Primary (citable) accession number: B0R685

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	April 8, 2008
Last modified:	January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program