B0R596 (RNP3_HALS3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 3
Short name=RNase P component 3
EC=3.1.26.5

Gene names

Name:	rnp3
Ordered Locus Names:	OE2834R

Organism

Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) [Complete proteome] [HAMAP]

Taxonomic identifier

478009 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00756
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00756
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: InterPro
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 232	232	Ribonuclease P protein component 3 HAMAP MF_00756		PRO_1000194590

Sequences

	Sequence		Length	Mass (Da)
	B0R596 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 4B3D0DF9B3DBBE41	FASTA	232	24,884
	10 20 30 40 50 60 MYEAVCAHPD GDSTVARLAA TAASAGYDGI VVRNWGATSA DPDAVGADTD ADVVRGTTVS 70 80 90 100 110 120 VTDRAGASER IRRRRENAVV VAARASSPSL NRFVAESERV DVLAAPMADG GDVNHVIVKA 130 140 150 160 170 180 ARTHGVRLEF DFAGVLRASG GDRVQALRGL RKLRELVEHY DAPFVVSGRP ASHLHVRSPR 190 200 210 220 230 ELVAVGAEIG FTDAQVRAGL REWTHLAARN RRRLSAEFIA PGVKRGRYEE DP

References

[1]

"Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1." Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K., Ruepp A., Soppa J., Tittor J., Oesterhelt D. Genomics 91:335-346(2008) [PubMed: 18313895] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29341 / DSM 671 / R1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM774415 Genomic DNA. Translation: CAP13913.1.
RefSeq	YP_001689261.1. NC_010364.1.
3D structure databases
ProteinModelPortal	B0R596.
ModBase	Search...
Protein-protein interaction databases
STRING	B0R596.
Proteomic databases
PRIDE	B0R596.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5952901.
GenomeReviews	Gene locus OE2834R in contig AM774415_GR.
KEGG	hsl:OE2834R.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG498067.
OMA	RFAVEQP.
PhylomeDB	B0R596.
ProtClustDB	CLSK758698.
Enzyme and pathway databases
BioCyc	HSAL478009:OE2834R-MONOMER.
Family and domain databases
HAMAP	MF_00756. RNase_P_3. [Tree]
InterPro	IPR016195. Pol/histidinol_Pase-like. IPR023539. RNase_P_comp-3. IPR002738. RNase_P_p30. [Graphical view]
KO	K03539.
Pfam	PF01876. RNase_P_p30. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP3_HALS3

Accession

Primary (citable) accession number: B0R596

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	April 8, 2008
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program