Skip Header

Contribute Send feedback
Read comments (?) or add your own

B0R558 (AROA_HALS3) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable 3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:OE2762R
OrganismHalobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) [Complete proteome] [HAMAP]
Taxonomic identifier478009 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 430430Probable 3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099704

Sequences

Sequence LengthMass (Da)Tools
B0R558 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 3A9D2E0BB4D459E5

FASTA43043,422
        10         20         30         40         50         60 
MHATVSPSRV RGRARAPPSK SYTHRALLAA GYADGETVVR DPLVSADTRA TARAVELLGG 

        70         80         90        100        110        120 
AAARENGDWV VTGFGSRPAI PDAVIDCANS GTTMRLVTAA AALADGTTVL TGDESLRARP 

       130        140        150        160        170        180 
HGPLLDALSG LGGTARSTRG NGQAPLVVDG PVSGGSVALP GDVSSQFVTA LLMAGAVTET 

       190        200        210        220        230        240 
GIETDLTTEL KSAPYVDITL DVLDAFGVGA SETAAGYRVR GGQAYAPSGA EYAVPGDFSS 

       250        260        270        280        290        300 
ASYLLAAGAL AAADGAAVVV EGMHPSAQGD AAIVDVLERM GADIDWDTES GVITVQRSEL 

       310        320        330        340        350        360 
SGVEVGVADT PDLLPTIAVL GAAADGTTRI TDAEHVRYKE TDRVAAMAES LSKLGASVEE 

       370        380        390        400        410        420 
RPDELVVRGG DTELSGASVD GRGDHRLVMA LAVAGLVADG ETTIAGSEHV DVSFPDFFEV 

       430 
LAGLGADTDG

« Hide

References

[1]"Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1."
Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K., Ruepp A., Soppa J., Tittor J., Oesterhelt D.
Genomics 91:335-346(2008) [PubMed: 18313895] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29341 / DSM 671 / R1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM774415 Genomic DNA. Translation: CAP13874.1.
RefSeqYP_001689222.1. NC_010364.1.

3D structure databases

ProteinModelPortalB0R558.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0R558.

Proteomic databases

PRIDEB0R558.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5953558.
GenomeReviewsGene locus OE2762R in contig AM774415_GR.
KEGGhsl:OE2762R.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMARLRIKEC.
PhylomeDBB0R558.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycHSAL478009:OE2762R-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_HALS3
AccessionPrimary (citable) accession number: B0R558
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents