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B0R548 (PGK_HALS3) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:OE_2745R
OrganismHalobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) [Complete proteome] [HAMAP]
Taxonomic identifier478009 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000096347

Regions

Nucleotide binding357 – 3604ATP By similarity
Region21 – 233Substrate binding By similarity
Region60 – 634Substrate binding By similarity

Sites

Binding site371Substrate By similarity
Binding site1171Substrate By similarity
Binding site1571Substrate By similarity
Binding site3321ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
B0R548 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 90CC881964915547

FASTA39841,046
        10         20         30         40         50         60 
MAIRTLDDLA AANRAIGVRV DINSPLTAAG GLADDARLRA HVDTLAELLA ADARVAVLAH 

        70         80         90        100        110        120 
QGRPGGDEFA RLERHADRLD ALLDAPVSYC DATFSTGARD AVADLAPGEA VVLENTRFYS 

       130        140        150        160        170        180 
EEYMAFAPER AADTALVDGL APALDAYVND AFAAAHRSQP SLVGFPEVLP SYAGRVMEAE 

       190        200        210        220        230        240 
LDALSGVADT PTPRTYVVGG AKVPDSVEVA AHALSHGLAD NVLVTGVVAN VFLAATGVDL 

       250        260        270        280        290        300 
GRASTDFIHE RDYGTEIARA ADLLAAHNDA LHLPVDVAVE RDGARCELST DALPPAGDEA 

       310        320        330        340        350        360 
VCDIGSDTVD AYADVLADSE TVVVNGPAGV FEDDLFADGT RGVFDAASEV EHSIVGGGDT 

       370        380        390 
AAAIRRFDIT GFDHVSTGGG AAINLLTDAD LPAVAALR 

« Hide

References

[1]"Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1."
Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K., Ruepp A., Soppa J., Tittor J., Oesterhelt D.
Genomics 91:335-346(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29341 / DSM 671 / R1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM774415 Genomic DNA. Translation: CAP13864.1.
RefSeqYP_001689212.1. NC_010364.1.

3D structure databases

ProteinModelPortalB0R548.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING478009.OE2745R.

Proteomic databases

PRIDEB0R548.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAP13864; CAP13864; OE_2745R.
GeneID5952870.
KEGGhsl:OE2745R.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227108.
KOK00927.
OMADMIFDIG.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycHSAL478009:GJVF-1006-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGK_HALS3
AccessionPrimary (citable) accession number: B0R548
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 8, 2008
Last modified: February 19, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways