B0R4C5 (B0R4C5_HALS3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Name:	purM EMBL CAP13590.1
Ordered Locus Names:	OE2292F

Organism

Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) [Complete proteome] [HAMAP]

Taxonomic identifier

478009 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Molecular function	Ligase RuleBase RU004370 EMBL CAP13590.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B0R4C5 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 15DDEF1027341B86	FASTA	331	33,562
	10 20 30 40 50 60 MTAGENADGD PDGLTYADAG VDIADSEAAT AALVDAASTG TDDTAYAGLV DLGDQYLALA 70 80 90 100 110 120 TDGVGTKLLV AEAVGDYSTV GIDCIAMNVN DLLAAGVEPA AFVDYLAVDE PNERRAAELG 130 140 150 160 170 180 DGLAAGADAA GVALVGGETA VMPDVVRGFD IAGTAAGVAT DAELFPGRAE AGDALVGFPS 190 200 210 220 230 240 AGIHSNGLTL AREAATRDGG YDEPYPYEGY ETVGDALLEP TRIYTHLLDA FREHGVHAAA 250 260 270 280 290 300 HITGGGWTNL DRMGGFRYEV SDPLPAQPVF DYVQDAGGVS DAEMHRTFNM GTGFVVALPE 310 320 330 DAAAALASQT DGEVVGRVAD GDGVSIRGLS L

References

[1]

"Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1." Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K., Ruepp A., Soppa J., Tittor J., Oesterhelt D. Genomics 91:335-346(2008) [PubMed: 18313895] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29341 / DSM 671 / R1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM774415 Genomic DNA. Translation: CAP13590.1.
RefSeq	YP_001688938.1. NC_010364.1.
3D structure databases
ProteinModelPortal	B0R4C5.
ModBase	Search...
Protein-protein interaction databases
STRING	B0R4C5.
Proteomic databases
PRIDE	B0R4C5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5952731.
GenomeReviews	Gene locus OE2292F in contig AM774415_GR.
KEGG	hsl:OE2292F.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG531222.
OMA	GIDMIAM.
PhylomeDB	B0R4C5.
ProtClustDB	PRK05385.
Family and domain databases
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
KO	K01933.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. PurM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B0R4C5_HALS3

Accession

Primary (citable) accession number: B0R4C5

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)