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B0R2Z8 (B0R2Z8_HALS3) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Inorganic pyrophosphatase HAMAP MF_00209
EC=3.6.1.1 HAMAP MF_00209
Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP MF_00209
Gene names
Name:ipp EMBL CAP13108.1
Synonyms:ppa HAMAP MF_00209
Ordered Locus Names:OE1407F
OrganismHalobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) [Complete proteome] [HAMAP]
Taxonomic identifier478009 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium

Protein attributes

Sequence length177 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP MF_00209

Cofactor

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP MF_00209

Subcellular location

Cytoplasm By similarity HAMAP MF_00209.

Sequence similarities

Belongs to the PPase family. HAMAP MF_00209

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP MF_00209
   LigandMagnesium HAMAP MF_00209
Metal-binding HAMAP MF_00209
   Molecular functionHydrolase HAMAP MF_00209 EMBL CAP13108.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphate-containing compound metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioninorganic diphosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding671Magnesium 1 By similarity HAMAP MF_00209
Metal binding721Magnesium 1 By similarity HAMAP MF_00209
Metal binding721Magnesium 2 By similarity HAMAP MF_00209
Metal binding1041Magnesium 1 By similarity HAMAP MF_00209

Sequences

Sequence LengthMass (Da)Tools
B0R2Z8 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: D23B03C1B094B2E7

FASTA17720,063
        10         20         30         40         50         60 
MANLWEDLET GPDAPDVIYA VVECLKGERN KYEYDKDIPG VVLDRVLHSN VHYPSDYGFI 

        70         80         90        100        110        120 
PQSYYDDGDP FDVLVLVEDQ TFPGCVIEAR PVALMEMDDD GEQDDKVIAV PEEDPRYDDV 

       130        140        150        160        170 
EDVDDLTDQQ KAEIAEFFET YKNLEADKET AVLGWGDAQA AKDAIEHAQD LYDEQFA

« Hide

References

[1]"Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1."
Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K., Ruepp A., Soppa J., Tittor J., Oesterhelt D.
Genomics 91:335-346(2008) [PubMed: 18313895] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29341 / DSM 671 / R1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM774415 Genomic DNA. Translation: CAP13108.1.
RefSeqYP_001688461.1. NC_010364.1.

3D structure databases

ProteinModelPortalB0R2Z8.
ModBaseSearch...

Protein-protein interaction databases

STRINGB0R2Z8.

Proteomic databases

PRIDEB0R2Z8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5952447.
GenomeReviewsGene locus OE1407F in contig AM774415_GR.
KEGGhsl:OE1407F.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG529150.
OMAPNDFNVI.
PhylomeDBB0R2Z8.
ProtClustDBCLSK511023.

Family and domain databases

HAMAPMF_00209. Inorganic_PPase.
[Tree]
InterProIPR008162. Pyrophosphatase.
[Graphical view]
Gene3DG3DSA:3.90.80.10. Pyrophosphatase. 1 hit.
KOK01507.
PANTHERPTHR10286. Pyrophosphatase. 1 hit.
PfamPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMSSF50324. Pyrophosphatase. 1 hit.
PROSITEPS00387. PPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB0R2Z8_HALS3
AccessionPrimary (citable) accession number: B0R2Z8
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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