B0R2Y7 (DCD_HALS3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	OE1384F

Organism

Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) [Complete proteome] [HAMAP]

Taxonomic identifier

478009 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium

Protein attributes

Sequence length	195 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 195	195	Probable deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000096428

Sequences

	Sequence		Length	Mass (Da)
	B0R2Y7 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 86CCDA4D48BC0C9D	FASTA	195	21,542
	10 20 30 40 50 60 MILSDQDILA RLADGDLAIE PLEDVDLQVQ PASVDVRLGR RFLEFERANV PCIHPNREDE 70 80 90 100 110 120 VDEYVTETVV EDGDEFILHP GDFVLGTTKE RVEVPRDLVA QVEGRSSLGR LAVVVHATAG 130 140 150 160 170 180 FIDPGFNGRV TLELSNLGKV PVALTPEMRI SQLVFTELTS PADRPYGDER GSKYQDQDGP 190 QASRIRGDRE FGGTQ

References

[1]

"Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1." Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K., Ruepp A., Soppa J., Tittor J., Oesterhelt D. Genomics 91:335-346(2008) [PubMed: 18313895] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29341 / DSM 671 / R1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM774415 Genomic DNA. Translation: CAP13097.1.
RefSeq	YP_001688450.1. NC_010364.1.
3D structure databases
ProteinModelPortal	B0R2Y7.
ModBase	Search...
Protein-protein interaction databases
STRING	B0R2Y7.
Proteomic databases
PRIDE	B0R2Y7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5952441.
GenomeReviews	Gene locus OE1384F in contig AM774415_GR.
KEGG	hsl:OE1384F.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG553199.
OMA	HTAAYID.
PhylomeDB	B0R2Y7.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	HSAL478009:OE1384F-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_HALS3

Accession

Primary (citable) accession number: B0R2Y7

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	April 8, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program