Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Halorhodopsin

Gene

hop

Organism
Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Light-driven chloride pump.1 Publication

Absorptioni

Abs(max)=578 nm1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei105Chloride 12 Publications1
Binding sitei111Chloride 22 Publications1
Binding sitei115Chloride 22 Publications1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionPhotoreceptor protein, Receptor, Retinal protein
Biological processIon transport, Transport
LigandChloride, Chromophore

Names & Taxonomyi

Protein namesi
Recommended name:
Halorhodopsin
Short name:
HR
Gene namesi
Name:hop
Ordered Locus Names:OE_1299R
OrganismiHalobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
Taxonomic identifieri478009 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
Proteomesi
  • UP000001321 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini22 – 25Extracellular1 Publication4
Transmembranei26 – 51Helical; Name=Helix AAdd BLAST26
Topological domaini52 – 57Cytoplasmic1 Publication6
Transmembranei58 – 81Helical; Name=Helix BAdd BLAST24
Topological domaini82 – 105Extracellular1 PublicationAdd BLAST24
Transmembranei106 – 127Helical; Name=Helix CAdd BLAST22
Topological domaini128 – 130Cytoplasmic1 Publication3
Transmembranei131 – 154Helical; Name=Helix DAdd BLAST24
Topological domaini155 – 157Extracellular1 Publication3
Transmembranei158 – 180Helical; Name=Helix EAdd BLAST23
Topological domaini181 – 192Cytoplasmic1 PublicationAdd BLAST12
Transmembranei193 – 216Helical; Name=Helix FAdd BLAST24
Topological domaini217 – 226Extracellular1 Publication10
Transmembranei227 – 255Helical; Name=Helix GAdd BLAST29
Topological domaini256 – 274Cytoplasmic1 PublicationAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PropeptideiPRO_00004289231 – 21Add BLAST21
ChainiPRO_000042892422 – 274HalorhodopsinAdd BLAST253

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei242N6-(retinylidene)lysine1

Interactioni

Subunit structurei

Homotrimer.2 Publications

Structurei

Secondary structure

1274
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi27 – 50Combined sources24
Turni51 – 53Combined sources3
Helixi58 – 81Combined sources24
Turni82 – 85Combined sources4
Beta strandi87 – 90Combined sources4
Turni96 – 99Combined sources4
Beta strandi100 – 104Combined sources5
Helixi106 – 127Combined sources22
Helixi131 – 153Combined sources23
Helixi158 – 180Combined sources23
Helixi182 – 189Combined sources8
Helixi193 – 216Combined sources24
Turni218 – 221Combined sources4
Helixi227 – 241Combined sources15
Helixi243 – 255Combined sources13
Helixi257 – 261Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1E12X-ray1.80A22-274[»]
2JAFX-ray1.70A1-274[»]
2JAGX-ray1.93A1-274[»]
5AHYX-ray2.15A20-274[»]
5AHZX-ray2.45A20-274[»]
5G36X-ray2.60A20-274[»]
ProteinModelPortaliB0R2U4
SMRiB0R2U4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000038084
KOiK04642
OMAiGRYLTWT
OrthoDBiPOG093Z08PM

Family and domain databases

InterProiView protein in InterPro
IPR001425 Arc/bac/fun_rhodopsins
IPR018229 Rhodopsin_retinal_BS
PANTHERiPTHR28286 PTHR28286, 1 hit
PfamiView protein in Pfam
PF01036 Bac_rhodopsin, 1 hit
PRINTSiPR00251 BACTRLOPSIN
SMARTiView protein in SMART
SM01021 Bac_rhodopsin, 1 hit
PROSITEiView protein in PROSITE
PS00950 BACTERIAL_OPSIN_1, 1 hit
PS00327 BACTERIAL_OPSIN_RET, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

B0R2U4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSITSVPGVV DAGVLGAQSA AAVRENALLS SSLWVNVALA GIAILVFVYM
60 70 80 90 100
GRTIRPGRPR LIWGATLMIP LVSISSYLGL LSGLTVGMIE MPAGHALAGE
110 120 130 140 150
MVRSQWGRYL TWALSTPMIL LALGLLADVD LGSLFTVIAA DIGMCVTGLA
160 170 180 190 200
AAMTTSALLF RWAFYAISCA FFVVVLSALV TDWAASASSA GTAEIFDTLR
210 220 230 240 250
VLTVVLWLGY PIVWAVGVEG LALVQSVGVT SWAYSVLDVF AKYVFAFILL
260 270
RWVANNERTV AVAGQTLGTM SSDD
Length:274
Mass (Da):28,874
Last modified:April 8, 2008 - v1
Checksum:i8FEDBBEDC717CD6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X04777 Genomic DNA Translation: CAB37866.1
AM774415 Genomic DNA Translation: CAP13054.1
PIRiA26161
RefSeqiWP_010902090.1, NC_010364.1

Genome annotation databases

EnsemblBacteriaiCAP13054; CAP13054; OE_1299R
GeneIDi5952411
KEGGihsl:OE_1299R

Similar proteinsi

Entry informationi

Entry nameiBACH_HALS3
AccessioniPrimary (citable) accession number: B0R2U4
Secondary accession number(s): P16102, Q9HSK9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 14, 2014
Last sequence update: April 8, 2008
Last modified: December 20, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health