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Protein
Submitted name:

Nociceptin receptor

Gene

Oprl1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: MGI
  2. neuropeptide binding Source: GO_Central
  3. nociceptin receptor activity Source: MGI

GO - Biological processi

  1. adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway Source: MGI
  2. G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger Source: GO_Central
  3. neuropeptide signaling pathway Source: GO_Central
  4. opioid receptor signaling pathway Source: MGI
  5. positive regulation of cytosolic calcium ion concentration Source: MGI
  6. synaptic transmission Source: GO_Central
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Nociceptin receptorImported
Gene namesi
Name:Oprl1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 2

Organism-specific databases

MGIiMGI:97440. Oprl1.

Subcellular locationi

GO - Cellular componenti

  1. integral component of plasma membrane Source: MGI
  2. neuron projection Source: GO_Central
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiB0R0B7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB0R0B7.
SMRiB0R0B7. Positions 43-141.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118797.
HOGENOMiHOG000199981.
HOVERGENiHBG106919.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001418. Opioid_rcpt.
IPR001420. X_opioid_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00384. OPIOIDR.
PR00547. XOPIOIDR.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B0R0B7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MESLFPAPFW EVLYGSHFQG NLSLLNETVP HHLLLNASHS AFLPLGLKVT
60 70 80 90 100
IVGLYLAVCI GGLLGNCLVM HTKMKTATNI YIFNLALADT LVLLTLPFQG
110 120 130 140
TDILLGFWPF GNALCKTVIA IDYYNMFTST FTLTAMSVDR Y
Length:141
Mass (Da):15,592
Last modified:April 8, 2008 - v1
Checksum:iBCB8DF3DD5DE32F2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei141 – 1411Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL845173 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000148334; ENSMUSP00000118664; ENSMUSG00000027584.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL845173 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliB0R0B7.
SMRiB0R0B7. Positions 43-141.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000148334; ENSMUSP00000118664; ENSMUSG00000027584.

Organism-specific databases

MGIiMGI:97440. Oprl1.

Phylogenomic databases

GeneTreeiENSGT00760000118797.
HOGENOMiHOG000199981.
HOVERGENiHBG106919.

Miscellaneous databases

ChiTaRSiOprl1. mouse.
NextBioi35545538.
SOURCEiSearch...

Gene expression databases

ExpressionAtlasiB0R0B7. baseline and differential.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001418. Opioid_rcpt.
IPR001420. X_opioid_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00384. OPIOIDR.
PR00547. XOPIOIDR.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB0R0B7_MOUSE
AccessioniPrimary (citable) accession number: B0R0B7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: February 4, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.